Protein Info for EX31_RS11430 in Rahnella sp. WP5

Annotation: SDR family oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 274 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF03446: NAD_binding_2" amino acids 3 to 90 (88 residues), 27.5 bits, see alignment E=3e-10 PF01370: Epimerase" amino acids 10 to 131 (122 residues), 23.1 bits, see alignment E=4.6e-09

Best Hits

Swiss-Prot: 65% identical to YEEZ_ECOLI: Protein YeeZ (yeeZ) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 99% identity to rah:Rahaq_1768)

Predicted SEED Role

"Nucleoside-diphosphate-sugar epimerases"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (274 amino acids)

>EX31_RS11430 SDR family oxidoreductase (Rahnella sp. WP5)
MKKVSIIGLGWLGMPLAMALASKGYQVVGSKTTPDGVDAARAVGIECFPLVFTPQMECAA
EDLDQLLNVDALIITLPARRTVEGSELYFQAVQLLTDSALAHNVKRIIFTSSTSVYGEGE
GVVREGSPLEPVTTSGKVLKELENWLHGLPNTSVDVLRLAGLVGGDRHPGRFMAGKTQVK
GGQHGVNLVHQDDVIAAIALLLSLPKGGHTYNLCAPAHPAKAEFYPALARQMGLEPPTFA
EQASAQKGKIVDGERICKELGFEYQHADPRTMPF