Protein Info for EX31_RS11375 in Rahnella sp. WP5

Annotation: HAMP domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 564 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details transmembrane" amino acids 192 to 214 (23 residues), see Phobius details PF02203: TarH" amino acids 1 to 176 (176 residues), 161 bits, see alignment E=4.2e-51 PF00672: HAMP" amino acids 216 to 263 (48 residues), 48.4 bits, see alignment 1.4e-16 PF00015: MCPsignal" amino acids 328 to 484 (157 residues), 199.5 bits, see alignment E=5.6e-63

Best Hits

Swiss-Prot: 71% identical to MCPS_KLEAK: Methyl-accepting chemotaxis serine transducer (tse) from Klebsiella aerogenes (strain ATCC 13048 / DSM 30053 / JCM 1235 / KCTC 2190 / NBRC 13534 / NCIMB 10102 / NCTC 10006)

KEGG orthology group: K05874, methyl-accepting chemotaxis protein I, serine sensor receptor (inferred from 100% identity to rah:Rahaq_1830)

Predicted SEED Role

"Methyl-accepting chemotaxis protein I (serine chemoreceptor protein)" in subsystem Bacterial Chemotaxis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (564 amino acids)

>EX31_RS11375 HAMP domain-containing protein (Rahnella sp. WP5)
MFNRMKVVTGIVILLVVFGALQLVSGGLFFKSLKTDKDNFTTSQQIRLQQAEFNASWIYL
LQTRNTLNRAGIRFMLDANQMGSGATVKELIDTATKDLQIADQHFASYQKIPADASQNPQ
FAADAKKQYQVLHDALSELIELIGLGRINDFFEQPTQQYQDNFEKAFVTYIDQNDRLYNE
AVKVSENSFTHAIWMLGTVLIVLAIFILLAWTGVQRILIHPLKNIVDTIRKIATGDLTHE
IVVKSRNEIGQLADSLKYMQDELIRTVSGVRHGADAIYSGASEISAGNSDLSSRTEQQAS
ALEETAASMEQLTATVKQNAENARQASQLALSASETAQKGGKVVANVVDTMNDIASSSKK
ITDITGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRTLAQRSAQAAKEIKGL
IDDSVSRINTGSVLAESAGETMHDMVNAVTRVTDIMGEITSASDEQSRGIEQVAQAITEM
DRVTQQNASLVEESASASAALEEQASLLTQSVAVFTLSQTANNNVRQNPASSARLSLLTP
NLSGSKAGKGGAQGTDLTENWETF