Protein Info for EX31_RS11250 in Rahnella sp. WP5

Annotation: amino acid ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 249 PF00005: ABC_tran" amino acids 16 to 174 (159 residues), 126.2 bits, see alignment E=2.2e-40 PF13304: AAA_21" amino acids 144 to 203 (60 residues), 33.4 bits, see alignment E=7.1e-12

Best Hits

Swiss-Prot: 49% identical to Y4TH_SINFN: Probable amino-acid ABC transporter ATP-binding protein y4tH (NGR_a01510) from Sinorhizobium fredii (strain NBRC 101917 / NGR234)

KEGG orthology group: K02028, polar amino acid transport system ATP-binding protein [EC: 3.6.3.21] (inferred from 99% identity to rah:Rahaq_1856)

Predicted SEED Role

"Amino acid ABC transporter, ATP-binding protein"

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.21

Use Curated BLAST to search for 3.6.3.21

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (249 amino acids)

>EX31_RS11250 amino acid ABC transporter ATP-binding protein (Rahnella sp. WP5)
MEINNLSKYYGAHKALDNVSLRIEPGTVTVILGPSGSGKSTLLRTINHLERVDEGFIQID
GDYIGYRRKGDTLYELKERAILKQRTHVGYVFQNFNLFPHMTVLDNIIEAPVVHGLLSRK
NAIARACELLDTVGLREKAHAWPRHLSGGQQQRIAIARALALNPKVMLFDEPTSALDPEL
VGEVLDVIKKLAQSGVTLVVVTHEIGFARQVADQVVFMVDGRVVESGAAAQVLERPVHAR
TQAFLEKVL