Protein Info for EX31_RS11215 in Rahnella sp. WP5

Annotation: TetR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 222 PF00440: TetR_N" amino acids 35 to 76 (42 residues), 34.1 bits, see alignment 1.8e-12 PF16925: TetR_C_13" amino acids 103 to 216 (114 residues), 152.7 bits, see alignment E=3.7e-49

Best Hits

Swiss-Prot: 50% identical to ACUR_RHOS4: Transcriptional regulator AcuR (acuR) from Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)

KEGG orthology group: None (inferred from 99% identity to rah:Rahaq_1863)

Predicted SEED Role

"Transcriptional regulator, TetR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (222 amino acids)

>EX31_RS11215 TetR family transcriptional regulator (Rahnella sp. WP5)
MMSAELSTEPDVPVKPRRGRPPRTAREFDDTREALIRSGLEVITETGYLSAGIDAVIKNI
AVPKGSFYHYFKSKQDFGMAVLTAYGSFFAHKLDKFLLRAELSPLQRIGAFVTHAGEGMA
KFEFRRGCLVGNLLQESPLLPEDFSQQLKTILGEWEGRVATCLEEARQAGDIASDMPPAQ
LAQIFWSGWEGAVMRAKLYRSAEPLDQFWAYFRHTLQSPVHS