Protein Info for EX31_RS10910 in Rahnella sp. WP5

Annotation: oligosaccharide MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 429 transmembrane" amino acids 12 to 36 (25 residues), see Phobius details amino acids 47 to 66 (20 residues), see Phobius details amino acids 78 to 99 (22 residues), see Phobius details amino acids 105 to 126 (22 residues), see Phobius details amino acids 146 to 165 (20 residues), see Phobius details amino acids 171 to 190 (20 residues), see Phobius details amino acids 222 to 239 (18 residues), see Phobius details amino acids 259 to 283 (25 residues), see Phobius details amino acids 291 to 309 (19 residues), see Phobius details amino acids 320 to 338 (19 residues), see Phobius details amino acids 350 to 370 (21 residues), see Phobius details amino acids 382 to 402 (21 residues), see Phobius details PF01306: LacY_symp" amino acids 7 to 404 (398 residues), 368.4 bits, see alignment E=6.8e-114 TIGR00882: oligosaccharide:H+ symporter" amino acids 10 to 401 (392 residues), 365.2 bits, see alignment E=2e-113 PF12832: MFS_1_like" amino acids 12 to 383 (372 residues), 80 bits, see alignment E=2.8e-26 PF07690: MFS_1" amino acids 18 to 244 (227 residues), 47.1 bits, see alignment E=2.5e-16

Best Hits

KEGG orthology group: K02532, MFS transporter, OHS family, lactose permease (inferred from 100% identity to rah:Rahaq_1933)

Predicted SEED Role

"Sucrose permease, major facilitator superfamily" in subsystem Sucrose utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (429 amino acids)

>EX31_RS10910 oligosaccharide MFS transporter (Rahnella sp. WP5)
MKAIKTASKTAYYKMSSFIFLYFFTWSSSFGLYALWLGQKAGLDSVSIGTVFAVNGVFAV
IMKPVYGYIMDKIGMSKSLLYFVVLVSALMAPFFIFVYQPLLDSHLMLGIIVGALYLSLG
WYAGVAASESYADRFSRLYHMEFGQVRMWGSLGWALAASFSGVLFNLSPAWNFGLSSATS
LVMLAVLLSLKIGDEELKDNDVISQQKIVFSDVILLLKNRKFWMFSLYVAGVAWMMFVAE
QQFSRYFVTFFDTKEQGNAWYGYLSTVQSGLEFLMMMVIPFLVNYFGAKKSLLLVGALVG
LRLIASGLTNDPLLISIIKPFYGLEIALLLVSVFKYIAEHFSKRVNATMYLLGYQAMIYV
GSIVVAPPAGYFYDRIGFEHTYLIMGGIALCFTLISAFTLSACHSLRSGTPVPAEQVEVE
TIGMEREKV