Protein Info for EX31_RS10850 in Rahnella sp. WP5

Annotation: mechanosensitive ion channel family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 808 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details transmembrane" amino acids 216 to 236 (21 residues), see Phobius details amino acids 257 to 281 (25 residues), see Phobius details amino acids 300 to 317 (18 residues), see Phobius details amino acids 335 to 353 (19 residues), see Phobius details amino acids 365 to 387 (23 residues), see Phobius details amino acids 409 to 433 (25 residues), see Phobius details amino acids 444 to 468 (25 residues), see Phobius details amino acids 489 to 513 (25 residues), see Phobius details amino acids 543 to 562 (20 residues), see Phobius details amino acids 583 to 607 (25 residues), see Phobius details amino acids 614 to 633 (20 residues), see Phobius details PF12607: DUF3772" amino acids 140 to 201 (62 residues), 54.1 bits, see alignment 2e-18 PF21088: MS_channel_1st" amino acids 589 to 630 (42 residues), 28.4 bits, see alignment 2.7e-10 PF00924: MS_channel_2nd" amino acids 632 to 697 (66 residues), 77.5 bits, see alignment E=1.4e-25 PF21082: MS_channel_3rd" amino acids 706 to 787 (82 residues), 30.1 bits, see alignment E=1.1e-10

Best Hits

KEGG orthology group: None (inferred from 100% identity to rah:Rahaq_1946)

Predicted SEED Role

"potassium efflux system KefA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (808 amino acids)

>EX31_RS10850 mechanosensitive ion channel family protein (Rahnella sp. WP5)
MQKMLRVPLLLALLSCLLITPVLSQADESTGQPATAEQPVKVNVTTALPALQKRLDQLKQ
QVSSAKTDKKFTGLTDAAQKLAEDADKLTGALTPDLAQVQAQLDVLGPAPAPGTITETPQ
VISQRNKLNNSKTLLTTQIEQTKAISLGAQNLSSQIAGLRRDALKTQIALNTGSILGGNF
WAPLITPNDDDAARFDDFGSQVKDAWMQAWSEEWRIGTAIYLLLALVIGLAGRRVLDRPM
NWILPRWLPQGRFRRSFLACFTTLSTTLTLGISVQLLGYIFTRLPDTSPWVTEFAGQLVE
LTYFSAVIAGLGIALLSNNHPSWRLPGIADPLAKTLASFPVLLAGFIFLFGIIEQLNNLV
GASVSATLFGNGLAALLVALNCLIAPVRINRMRRKMKAEGEQTEARSTLAGLIHLVISLT
AFVILMALLIGYIPLARFVTFELLWIGLVVSCLYLLIHFVVDLCESLFAPTTHSGKILKS
TLSVNDRHLSLAATLFSAIGKTGLLLMAAVALLNGTFGTTTPLELLAKIVDIWGGKGLES
MNIIPAHAVNAVLCLVVGWYILRSARRWLDNDFLPKTMMDRGMRASLVTLFTNVGYVLII
LLTLSSLGIEWNKLAWIVSALSVGIGFGLQEIVKNFISGLILLTERPVKVGDLISISGVE
GDIRRINVRATEIQLSDKSTVIVPNSQLISQNVRNATMGNAQGVATITLTFPLDIDPEQV
KTLLLEAYNLHESILENPPASVSFKELGPTGIVLSVTGFVNSPRMVSGTRSDLLYEILKM
LRAAGISLSQTQTMILEKPAERIVPVEE