Protein Info for EX31_RS10810 in Rahnella sp. WP5

Annotation: AraC family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 313 PF06719: AraC_N" amino acids 31 to 179 (149 residues), 144.1 bits, see alignment E=3.8e-46 PF00165: HTH_AraC" amino acids 201 to 242 (42 residues), 27.8 bits, see alignment 3.2e-10 PF12833: HTH_18" amino acids 214 to 289 (76 residues), 73.7 bits, see alignment E=1.9e-24

Best Hits

Swiss-Prot: 45% identical to YQHC_ECOLI: Uncharacterized HTH-type transcriptional regulator YqhC (yqhC) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 99% identity to rah:Rahaq_1954)

Predicted SEED Role

"Hypothetical transcriptional regulator YqhC" in subsystem D-gluconate and ketogluconates metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (313 amino acids)

>EX31_RS10810 AraC family transcriptional regulator (Rahnella sp. WP5)
MTFPSLTVTEQMIALLDQLTPHEGYNLTTLADVRFLRSNRPLLRTPVLYEPGIVIVVQGR
KRGFLGNDVYLYDAQHYLTVSVPVPFTMETDATASEPMLAIYLRLDFSLAAELMLQLDTY
DAPQPESPKSMVSSLMDDAMRACVLRFLQVMASPLDAKILGRAMMRELYYRVLTGAQGGT
LRSALTLQGQFGKVVKALRKLHAEYHSHLDVNALAKEAGMSLPTFHSHFKTVTDTSPMQY
LKSTRLHQARLLMLRNNLTASAASAQVGYESVSQFSREFKRLFGLTPAREVARMRQNFSL
PAPSTPSDFISSH