Protein Info for EX31_RS10430 in Rahnella sp. WP5

Annotation: 5-oxoprolinase subunit PxpB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02682: CT_C_D
  • amino acids 24 to 221 (198 residues), 213.8 bits, E=1.1e-67
• TIGR00370: sensor histidine kinase inhibitor, KipI family
  • amino acids 28 to 230 (203 residues), 177.9 bits, E=8e-57

Best Hits

Swiss-Prot: 38% identical to PXPB_HAEIN: 5-oxoprolinase subunit B (pxpB) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: None (inferred from 100% identity to rah:Rahaq_2709)

Predicted SEED Role

"Allophanate hydrolase 2 subunit 1 (EC 3.5.1.54)" (EC 3.5.1.54)

MetaCyc Pathways

• allantoin degradation IV (anaerobic) (8/9 steps found)
• uracil degradation III (5/5 steps found)
• L-arginine degradation V (arginine deiminase pathway) (4/4 steps found)
• L-citrulline degradation (3/3 steps found)
• urea degradation I (3/3 steps found)
• superpathway of allantoin degradation in yeast (5/6 steps found)
• cyanate degradation (2/3 steps found)
• cyanuric acid degradation II (3/5 steps found)
• cyanuric acid degradation I (2/5 steps found)
• superpathway of atrazine degradation (3/8 steps found)

KEGG Metabolic Maps

• Arginine and proline metabolism
• Atrazine degradation
• Urea cycle and metabolism of amino groups

Isozymes

Compare fitness of predicted isozymes for: 3.5.1.54

Use Curated BLAST to search for 3.5.1.54

Protein Sequence (236 amino acids)

>EX31_RS10430 5-oxoprolinase subunit PxpB (Rahnella sp. WP5)
MITASHEAPSRASFILASQGDNIKISTIGSRAWLIEAPGDFDLPAQRRIWSLAVALRARD
DIESLIPGVTNLLVLFRQTPADYDATFALLVAAWDQAQAVHPQGKLIEIPVIYGGEHATD
LDAVCQHTGLSPREVIRRHSEGCYTVFSLGSAPGFGYLHGLDPSLATPRKKVPSLNMLKG
TVTIGGAQTGISALTGPNGWNAIGFAELTLFDPQAENPALMAPGDSVRFLPERIEL