Protein Info for EX31_RS09755 in Rahnella sp. WP5

Annotation: xylose ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 501 TIGR02633: D-xylose ABC transporter, ATP-binding protein" amino acids 1 to 495 (495 residues), 824.8 bits, see alignment E=1.1e-252 PF00005: ABC_tran" amino acids 14 to 165 (152 residues), 104.5 bits, see alignment E=7.6e-34 amino acids 272 to 426 (155 residues), 81.2 bits, see alignment E=1.2e-26

Best Hits

Swiss-Prot: 76% identical to XYLG_YERPN: Xylose import ATP-binding protein XylG (xylG) from Yersinia pestis bv. Antiqua (strain Nepal516)

KEGG orthology group: K10545, D-xylose transport system ATP-binding protein [EC: 3.6.3.17] (inferred from 99% identity to rah:Rahaq_2577)

MetaCyc: 73% identical to xylose ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
ABC-33-RXN [EC: 7.5.2.10, 7.5.2.13]

Predicted SEED Role

"D-xylose transport ATP-binding protein XylG" in subsystem Xylose utilization

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.17

Use Curated BLAST to search for 3.6.3.17 or 7.5.2.10 or 7.5.2.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (501 amino acids)

>EX31_RS09755 xylose ABC transporter ATP-binding protein (Rahnella sp. WP5)
MRNITKRFGAVKAVDNISLTLSAGEVLSLCGENGSGKSTLMKVLCGIYPQGTFEGEIYFS
GERLTAKGIRDTEQKGIAIIHQELALVKQLSVLENMFLGNEWGSYGLLDTDKMYLRCQRM
LAQVKLNIDPHTLVGELGLGQRQLVEIAKALNKQVRLLVLDEPTASLTESETAILLDIIR
DLRHHDIACIYISHKLNEVKAISDKLCVIRDGRHIATCNAAGTSEKEIIAMMVGRELTEL
FPPRERQIGKEILRVENLTAWHPVNRHIKRVDNAGFTLREGEVLGVAGLVGAGRTEMMEC
LFGVYPGRWSGDIWLQGEKVQITGCRDAMRRGLAMVPEDRKRDGIVPVMAVGSNITLAAL
SQFSAGGVLREAEEQHSISESVKQLKIKTSSPELAIGRLSGGNQQKAILARCLLLKPKIL
ILDEPTRGIDVGAKHEIYKLIGQLAAQGMAIIVISSELPEVLGLSDRVVVMHLGQVKACL
DNNNLSQEQVMEAALRSESYV