Protein Info for EX31_RS09190 in Rahnella sp. WP5

Annotation: ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 291 transmembrane" amino acids 30 to 51 (22 residues), see Phobius details amino acids 94 to 118 (25 residues), see Phobius details amino acids 129 to 149 (21 residues), see Phobius details amino acids 154 to 172 (19 residues), see Phobius details amino acids 203 to 225 (23 residues), see Phobius details amino acids 259 to 279 (21 residues), see Phobius details PF12911: OppC_N" amino acids 20 to 67 (48 residues), 43.3 bits, see alignment 2.8e-15 PF00528: BPD_transp_1" amino acids 108 to 289 (182 residues), 118.3 bits, see alignment E=3.4e-38

Best Hits

Swiss-Prot: 46% identical to GSID_SHIF8: Glutathione transport system permease protein GsiD (gsiD) from Shigella flexneri serotype 5b (strain 8401)

KEGG orthology group: K02034, peptide/nickel transport system permease protein (inferred from 99% identity to rah:Rahaq_2407)

MetaCyc: 45% identical to glutathione ABC transporter membrane subunit GsiD (Escherichia coli K-12 substr. MG1655)
RXN0-11 [EC: 7.4.2.10]

Predicted SEED Role

"Putative glutathione transporter, permease component" in subsystem Utilization of glutathione as a sulphur source

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.10

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (291 amino acids)

>EX31_RS09190 ABC transporter permease (Rahnella sp. WP5)
MSVSVISVTTSLPAREPNRVLSKFLRNKSAVTGAVLVITFALLALLAPWISPFDPIKADF
MAVRKAPSALHWLGTDELGRDILSRLFWGARTSLMAGCVSVIIAIVIGVPLGLIAGFWQG
WLDSVISRVVEALLSCPFLVLAIALGAFLGPSLGNAMIAIGLSSMPIFARLTRAQVMSIR
NEEYIEGARAIGLPDRWILWRYVLPNVLSPILVQATLAIASAIITEASLSFLGLGQQPPD
ASWGAMLNTARSFLEQSPWMSIFPGLAIFLTVQGFNLLGDGLRDALDPRSE