Protein Info for EX31_RS08320 in Rahnella sp. WP5

Annotation: HTH-type transcriptional regulator MalT

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 908 PF17874: TPR_MalT" amino acids 456 to 788 (333 residues), 362.3 bits, see alignment E=2.7e-112 PF00196: GerE" amino acids 842 to 895 (54 residues), 68.7 bits, see alignment 2.6e-23

Best Hits

Swiss-Prot: 74% identical to MALT_ENT38: HTH-type transcriptional regulator MalT (malT) from Enterobacter sp. (strain 638)

KEGG orthology group: K03556, LuxR family transcriptional regulator, maltose regulon positive regulatory protein (inferred from 86% identity to ebi:EbC_44730)

MetaCyc: 73% identical to DNA-binding transcriptional activator MalT (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"Transcriptional activator of maltose regulon, MalT" in subsystem Maltose and Maltodextrin Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (908 amino acids)

>EX31_RS08320 HTH-type transcriptional regulator MalT (Rahnella sp. WP5)
MLIPSKLSRPVRQQNTVVRERLLTKLSTAPNYRLTLVASPAGYGKTTLVAHWAAGKSDLG
WYSLDESDNQPERFASYLIAAVQQACGGHCIKSEALSLKHQYASLPALFAQLFVELSDWH
SPLLLVIDDYHLISNDAIHEGMRFFLRHQPENLSLVVLSRTLPPLGIANMRVRDQLLELN
ASHLAFTHPETQQFFDNRLKDPIDQADSSRLCDEVAGWATALQLIALSARQSSHPSQHST
QQSARKLAGLNASHLSEYLVDEVLDRVDAPTRDFLLRCSLLRSMNDALIVRLTGSENGQQ
RLEELERQGLFINRMDDSGEWFNFHPLFATFLRQRCQWELASELPAIHRAAAEGWLAQGF
PAEAIHHALGAEDTNLLRDILLQHAWALFNQSELALLEECLAALPYDRLIQNPKLVLLQA
WLAQSQHRYAEVEVLLARAESEMKQHNIVMEQALAAEFDALRAQVAINDGRQDEAEKLAT
EALRYLPYESYYSRIVATSVTGEIQHCKGDLTRALPLMQQTEQIARRYEAYHYALWALLQ
QSEILIAQGFLQAAFEMQDRAFELVREQHLEQLPMHEFLLRLRSQLLWSWSRLDDAEEAA
REGLNVLSNFQPQQQLQCLAMLAKCSLARGQLDNAHHHLQRCEALLKTGQYHIDWLTNTD
KPRVIYWQMIGDKNAARQWLQQARKPDMADNHFQQGQWRNIARVQILLEQFDEAEVVLDE
LNQNARQLRLTSDLNRNLLLSNLLYWQTGRKSDAQKALIEALALANRTGFVSHFVIEGEM
MAQQLRQLIQLNLLPELEQRRAQQILREINQHHRHKFAHFDEGFVNKLLTHPQVPELIRT
SPLTQREWQVLGLIYSGYSNDQIAGELDVASTTIKTHIRNLYQKLGVAHRQEAVQQAQHL
LQVMGYGA