Protein Info for EX31_RS08280 in Rahnella sp. WP5

Annotation: maltose operon protein MalM

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 298 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF07148: MalM" amino acids 69 to 202 (134 residues), 180.7 bits, see alignment E=5.4e-58

Best Hits

Swiss-Prot: 56% identical to MALM_ECOLI: Maltose operon periplasmic protein (malM) from Escherichia coli (strain K12)

KEGG orthology group: K05775, maltose operon periplasmic protein (inferred from 99% identity to rah:Rahaq_0542)

Predicted SEED Role

"Maltose operon periplasmic protein MalM" in subsystem Maltose and Maltodextrin Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (298 amino acids)

>EX31_RS08280 maltose operon protein MalM (Rahnella sp. WP5)
MKKNLLSLCLSLSLLAAAPAVVNAAQNDANTAPAISSQTLRNLSWTPLVPPVTQDVTLGT
SSAEINQGEIQGAVGAFALPADRGSLEITLTSIATGKTVYAPNVLVLDEQMRPAAFYPSS
YFPYQKPGIVSSDRLEGTLKLTPALGQKQIYLLVYTTRQDLAETTQMVNPAKAFAAGVGN
AVPDIPDPIARHTPTGTLSLKVTAEQKTGNVMIGQIFPSSAPAAAAPVVVGSTQAPAPAA
APAKPSEPMLSDSETYFNDAIKKAVKAGDVDKALKLLDEAERLGSKTARKTFIESVKH