Protein Info for EX31_RS07990 in Rahnella sp. WP5

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 447 transmembrane" amino acids 21 to 37 (17 residues), see Phobius details amino acids 60 to 81 (22 residues), see Phobius details amino acids 90 to 134 (45 residues), see Phobius details amino acids 156 to 177 (22 residues), see Phobius details amino acids 183 to 203 (21 residues), see Phobius details amino acids 255 to 279 (25 residues), see Phobius details amino acids 292 to 317 (26 residues), see Phobius details amino acids 329 to 346 (18 residues), see Phobius details amino acids 352 to 374 (23 residues), see Phobius details amino acids 382 to 409 (28 residues), see Phobius details amino acids 415 to 437 (23 residues), see Phobius details PF07690: MFS_1" amino acids 27 to 317 (291 residues), 160.1 bits, see alignment E=7.4e-51 TIGR00893: D-galactonate transporter" amino acids 29 to 437 (409 residues), 466.3 bits, see alignment E=4.2e-144

Best Hits

Swiss-Prot: 79% identical to GARP_ECOLI: Probable galactarate transporter (garP) from Escherichia coli (strain K12)

KEGG orthology group: K12299, MFS transporter, ACS family, probable galactarate transporter (inferred from 100% identity to rah:Rahaq_0653)

MetaCyc: 79% identical to galactarate/D-glucarate transporter GarP (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-203; TRANS-RXN0-204; TRANS-RXN0-523

Predicted SEED Role

"D-galactarate permease" in subsystem D-galactarate, D-glucarate and D-glycerate catabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (447 amino acids)

>EX31_RS07990 MFS transporter (Rahnella sp. WP5)
MNIQSQSGTIAQSKVRTHIRYYILLIIFLITAVNYADRATLSIAGTEVARELGLDAADMG
QIFAAFGWAYLIMQLPGGWLLDRFGSKKVYTYSLFFWSLFTLLQGFVGWFPLAYGALTLF
MLRFMLGFSEAPSFPANARIVAAWFPTTERGTASAIFNSAQYFSLALFSPLLGWLTYAWG
WEHVFIVMGVLGFVLTLVWIKFIHNPPEHPHISKSELEYLTDGGAVVDIDHKKTDSAKSG
PKWSYVRQMLSSRMMLGIFFGQYFINSITWFFLTWFPIYLVQEKGMSILKVGMIAAIPAL
CGFAGGVLGGVFSDFLIRRGYSLTVARKIPIVLGMLLATSIILCNYTDNNVLVVTLMALA
FFGKGFGALGWPVIADTAPKEVIGLCGGIFNVFGNVASIVTPLVIGYIVKGLHSFNMALI
FVGCSALMAMLCYLLVVGDIKRLELKK