Protein Info for EX31_RS07890 in Rahnella sp. WP5

Annotation: aminopeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 345 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF04389: Peptidase_M28" amino acids 105 to 324 (220 residues), 86.3 bits, see alignment E=2.4e-28 PF01546: Peptidase_M20" amino acids 119 to 200 (82 residues), 24.6 bits, see alignment E=2.1e-09

Best Hits

Swiss-Prot: 54% identical to IAP_ECOLI: Alkaline phosphatase isozyme conversion protein (iap) from Escherichia coli (strain K12)

KEGG orthology group: K09612, alkaline phosphatase isozyme conversion protein [EC: 3.4.11.-] (inferred from 99% identity to rah:Rahaq_0674)

MetaCyc: 54% identical to alkaline phosphatase isozyme conversion protein (Escherichia coli K-12 substr. MG1655)
3.4.11.-

Predicted SEED Role

"Alkaline phosphatase isozyme conversion protein precursor (EC 3.4.11.-)" (EC 3.4.11.-)

Isozymes

Compare fitness of predicted isozymes for: 3.4.11.-

Use Curated BLAST to search for 3.4.11.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (345 amino acids)

>EX31_RS07890 aminopeptidase (Rahnella sp. WP5)
MFSFLRMKRTLLALSLSCVCMGHAMAASAPLPPVGMIASQQIRHIATYFPGRMAGSPAEL
IAADYLNQQFNKLGYTSDLRGFDTRYLYTSNAGKKNWQNIHATSVIAARAGEVPQQIIVM
AHFDTYVPQSDSDTNHNLGGLTLQGVDDNASGVSVMLELAERMQAIPTHYSLRFVALSAE
ETGAKGAEDFVNRMSAEEKKNTLLVINLNSLITGDRLYFNSGANTSVAVAKLTRIRALNI
AHSLGIPAESHEGVHCCDGIKALDDARLPLLNVTATNYALGKKDGLQQRAITSHFPLGTT
RYQSQFDNLQYLDKALPGRIEKRSRDTVKVLFPLLKDLAKPAKHA