Protein Info for EX31_RS06735 in Rahnella sp. WP5

Annotation: HutD family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 193 PF05962: HutD" amino acids 11 to 168 (158 residues), 159 bits, see alignment E=7.3e-51

Best Hits

Swiss-Prot: 46% identical to VES_ESCF3: Protein Ves (ves) from Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0568-73)

KEGG orthology group: K09975, hypothetical protein (inferred from 98% identity to rah:Rahaq_2159)

Predicted SEED Role

"Conserved hypothetical protein (perhaps related to histidine degradation)" in subsystem Histidine Degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (193 amino acids)

>EX31_RS06735 HutD family protein (Rahnella sp. WP5)
MIAWQHFTFDDLPVSPWRNGGGETREIFSFPAGGHDFDWRASIATIAQDGPFSAFPGIDR
SITLLSGEGVHLQAQPDVDHLLVVAGEPFAFSGDTALHARLMGGVTTDFNIMTRRTECAA
RVIAAREHLTVTREKGGVIYVISGMWQLADGPLLRAGEGYYWSETAAQSQQGSVSLTPVA
QQQRCLLLWAAIS