Protein Info for EX31_RS06700 in Rahnella sp. WP5

Annotation: UDP-forming cellulose synthase catalytic subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 871 transmembrane" amino acids 30 to 48 (19 residues), see Phobius details amino acids 80 to 96 (17 residues), see Phobius details amino acids 148 to 166 (19 residues), see Phobius details amino acids 172 to 189 (18 residues), see Phobius details amino acids 196 to 215 (20 residues), see Phobius details amino acids 227 to 251 (25 residues), see Phobius details amino acids 521 to 541 (21 residues), see Phobius details amino acids 544 to 569 (26 residues), see Phobius details amino acids 640 to 658 (19 residues), see Phobius details amino acids 664 to 689 (26 residues), see Phobius details TIGR03030: cellulose synthase catalytic subunit (UDP-forming)" amino acids 148 to 828 (681 residues), 926.6 bits, see alignment E=4e-283 PF13641: Glyco_tranf_2_3" amino acids 274 to 499 (226 residues), 76.7 bits, see alignment E=7.4e-25 PF00535: Glycos_transf_2" amino acids 276 to 446 (171 residues), 86.7 bits, see alignment E=5.4e-28 PF13506: Glyco_transf_21" amino acids 331 to 498 (168 residues), 40 bits, see alignment E=9.2e-14 PF13632: Glyco_trans_2_3" amino acids 355 to 559 (205 residues), 71.1 bits, see alignment E=3.6e-23 PF03552: Cellulose_synt" amino acids 444 to 571 (128 residues), 49.7 bits, see alignment E=7e-17 PF07238: PilZ" amino acids 693 to 789 (97 residues), 48.1 bits, see alignment E=3.8e-16

Best Hits

Swiss-Prot: 63% identical to BCSA_SALTY: Cellulose synthase catalytic subunit [UDP-forming] (bcsA) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K00694, cellulose synthase (UDP-forming) [EC: 2.4.1.12] (inferred from 65% identity to ebi:EbC_43920)

MetaCyc: 69% identical to cellulose synthase catalytic subunit (Escherichia coli K-12 substr. MG1655)
Cellulose synthase (UDP-forming). [EC: 2.4.1.12]

Predicted SEED Role

"Cellulose synthase catalytic subunit [UDP-forming] (EC 2.4.1.12)" (EC 2.4.1.12)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.1.12

Use Curated BLAST to search for 2.4.1.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (871 amino acids)

>EX31_RS06700 UDP-forming cellulose synthase catalytic subunit (Rahnella sp. WP5)
MNRVLNLFLVPPVVFELQNRYRYYRASHSSRTAAGVMIFCVALSWLFLRFESPVWQRVKA
QRTRWYPQISPSRPRLADPLRYIVQSLWLLIILPAESRRGRVIHTRWPQQLRKKIHLWLE
LLPEQVTHSPLEIKVTRRIGKMSRLGKRILVWMTALVALTLAMFCISQPFSYIAQFVFVM
LLWSIAMIIRRIPGRFPALMMIVLSLTISCRYLWWRYTSTLNWEDPLSLICGLLLLGAET
YSWTVLVLGYIQTLWPLNRKPVPMPADVSTWPTVDLLIPTYNEDLSVVKPTLYAALGLDW
PRDKLTIYLLDDGNRQEFADFAHEIGVKYIARETRENAKAGNINNALKQAKSQLVAIFDC
DHVPTRSFLQLTVGWFFKDKKLSMLQTPHHFFSPDPFERNLGRMRRTPNEGELFYGLVQD
GNDLWDASFFCGSCAVLRRDVLDEIGGIAVETVTEDAHTSLRMHRHGYTSAYIRIPQAAG
LATESLSAHISQRIRWARGMVQIFRLDNPMFGKGLKLAQRLCYANAMLHFLAGIPRLIFL
TAPLAFLLLHAYIIYAPAVAIALYVLPHMIHASLTNSRVQGKYRHSFWNEIYETVLAWYI
ARPTTVALFNPHAGAFNVTAKGGLNKHAYVDWKISRPYQILMLLNLAGLFFGAYRIVYGR
PDEILTVLVSMAWVIYNMIILGGAIAVAFESKQVRQAHRVEARMPASLLKPDGHIYVCTI
QDYSDNGVGLETPSASQFHAGDNVTLLLHRGQQEYTFPMQISRVFGESIGMQLLPLTTQQ
HIDFIQCTFARADSWVLREDNFPEDKPMESLREVLGLGIRGYLRMLDIAPQRYRPLASGT
RTFGRWLLSFAPRNPPLAVQPDEYNLMMTKQ