Protein Info for EX31_RS05610 in Rahnella sp. WP5

Annotation: urea carboxylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1209 PF00289: Biotin_carb_N" amino acids 1 to 109 (109 residues), 144.8 bits, see alignment E=5.6e-46 TIGR02712: urea carboxylase" amino acids 2 to 1205 (1204 residues), 1975.9 bits, see alignment E=0 PF02786: CPSase_L_D2" amino acids 116 to 319 (204 residues), 207.8 bits, see alignment E=5.6e-65 PF07478: Dala_Dala_lig_C" amino acids 145 to 291 (147 residues), 42.6 bits, see alignment E=2e-14 PF02785: Biotin_carb_C" amino acids 336 to 440 (105 residues), 122.5 bits, see alignment E=3.5e-39 TIGR00724: biotin-dependent carboxylase uncharacterized domain" amino acids 448 to 772 (325 residues), 336.1 bits, see alignment E=1.8e-104 PF02626: CT_A_B" amino acids 472 to 751 (280 residues), 330.2 bits, see alignment E=4.4e-102 PF02682: CT_C_D" amino acids 808 to 1025 (218 residues), 120.9 bits, see alignment E=2.4e-38 PF00364: Biotin_lipoyl" amino acids 1146 to 1203 (58 residues), 57.5 bits, see alignment 3.9e-19

Best Hits

Predicted SEED Role

"Urea carboxylase (EC 6.3.4.6)" in subsystem Urea decomposition (EC 6.3.4.6)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 6.3.4.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1209 amino acids)

>EX31_RS05610 urea carboxylase (Rahnella sp. WP5)
MFTTVLIANRGEIACRAIRTLKRLGVTSVAVYSDADRNAPHVTQADIAIALGGEKASESY
LMIDKILAAAKETDAQAIYPGYGFLSESAEFADACEAAGIAFIGPTAGQIREFGLKHRAR
ELAGAANVPMTPGTGLLDSIDDAVKAAAEIGYPIMLKSTAGGGGIGLTRCDNEEALRAAW
DSVKRLGEQFFRDAGVFLERFVDRARHVEVQIFGDGKGRVVALGERDCSLQRRNQKVVEE
TPAPDLPQASREALHRAAVQLGESVNYRSAGTVEFIYDAARDEFYFLEVNTRLQVEHPVT
EMVTGLDLIECMLNVAAGESPDWPAMEKAPQGASMEVRIYAEDPLKNFQPSPGVLTEVFF
PEDVRVDGWVSTGSEVSAFYDPMIAKLIVHGTDRQDALAKMSVALAATRLHGIATNIDYL
RQVVATPVFRNGEMWTRMLDSFDYSPNAIEVIAPGTYSSVQDYPGRLGYWDIGVPPSGPM
DDFAFRLANRIVGNHPDAAGLEFTLQGPTLRFHCDAVIALTGARCPATLDDEAVSYWQPV
DVKAGQTLTLGRATQGCRTYLAVRNGFDVPVYLGSRSTFALGQFGGHAGRTLRVADMLTV
SQPELAACTTPAPVGLPQAAENIVPPYGDIWNIGVLYGPHGAPDFFTKDAIDTFFAAEWQ
VHYNSNRLGVRLVGPKPQWARQDGGEAGLHPSNVHDCEYAIGAINFTGDFPVILTRDGPS
LGGFVCPVTIAKAELWKVGQVKPGDKIRFHPISFEQAQALERAQQGTLDSLMPVNAMALP
VPSLLPDTTASATILAALPATAERPSVEYRQAGDGYVLIEYGDNVLDLAVRMRIYLLMNA
IKAAGQQGIEELSPGVRSLQIRYDSRVLHQTALLQHLLTLENSLADVSQLKIPTRIVHMP
MAFEDSATLGAVERYQQTVRAEAPWLPNNVDFIQRTNGLASREDVKNIIFDASYLILGLG
DVYLGAPCAVPVDPRHRLLSSKYNPARTFTAEGTVGIGGMYMCIYGMDSPGGYQLVGRTL
PIWNKFLKNEQFKNGEPWLLHFFDQVRFYEVTEAELDIQREAFREGRAQIRIEETEFDFA
HYTQFLADNAADIADFRTRQTDAFTREVAHWHEAESAAVEAAANAVQLVEDDADQDGHLV
SADLNGNVWKILVQPGQQVEEGQPLIVVEAMKMELSVNAPCAGTVLKISCQQGRPVGPGD
ALLWLDTAV