Protein Info for EX31_RS05075 in Rahnella sp. WP5

Annotation: PTS cellobiose transporter subunit IIC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 442 transmembrane" amino acids 35 to 55 (21 residues), see Phobius details amino acids 82 to 103 (22 residues), see Phobius details amino acids 111 to 130 (20 residues), see Phobius details amino acids 142 to 161 (20 residues), see Phobius details amino acids 182 to 202 (21 residues), see Phobius details amino acids 208 to 225 (18 residues), see Phobius details amino acids 230 to 257 (28 residues), see Phobius details amino acids 288 to 311 (24 residues), see Phobius details amino acids 333 to 360 (28 residues), see Phobius details amino acids 391 to 413 (23 residues), see Phobius details TIGR00410: PTS system, lactose/cellobiose family IIC component" amino acids 16 to 427 (412 residues), 381.8 bits, see alignment E=2.3e-118 PF02378: PTS_EIIC" amino acids 33 to 352 (320 residues), 180.9 bits, see alignment E=1.7e-57

Best Hits

KEGG orthology group: K02761, PTS system, cellobiose-specific IIC component (inferred from 100% identity to rah:Rahaq_0192)

Predicted SEED Role

"PTS system, cellobiose-specific IIC component (EC 2.7.1.69)" in subsystem Beta-Glucoside Metabolism (EC 2.7.1.69)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.69

Use Curated BLAST to search for 2.7.1.69

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (442 amino acids)

>EX31_RS05075 PTS cellobiose transporter subunit IIC (Rahnella sp. WP5)
MSGLYQAMVNVIEKHITPLAGSVGQQRHVIAIRDGFIAALPFMIIGSFMLVFIFPPFSPD
TTMGFARGWLDLSLKYREQLMLPWYLSMGVMTFFISVGIGASLGKHYKLDPIMTGLLAFM
AFLLVAAPYHDKQISTQYFSGEGIFTAILTAIYAAEVYALLKRRNITIRLPKEVPTGVAR
SFEILIPVVAIVATLHPLNLFIQSTTGMIIPEAIMHLLAPLVSASDSLPAILISVFICQV
LWFAGIHGALIVTGIMNPFWMTNLALNQTALQAGAPLPHIYLQGFWDHYLLIGGVGSTLP
LAILLLCSKAVHLRTIGRMGVVPSFFNINEPILFGTPIIMNPVFFLPFTLVPMLNAIFAY
TATKLGWVAQVVSLTPWTTPAPIGASWAANWAFSPVIMCLFCMVLSAVMYYPFLKAYERT
LLKQEAEKALAQTAGNAVPANS