Protein Info for EX31_RS04850 in Rahnella sp. WP5

Annotation: Fe(2+) transporter permease subunit FeoB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 772 transmembrane" amino acids 102 to 121 (20 residues), see Phobius details amino acids 283 to 304 (22 residues), see Phobius details amino acids 310 to 332 (23 residues), see Phobius details amino acids 339 to 365 (27 residues), see Phobius details amino acids 394 to 412 (19 residues), see Phobius details amino acids 423 to 448 (26 residues), see Phobius details amino acids 455 to 474 (20 residues), see Phobius details amino acids 512 to 534 (23 residues), see Phobius details amino acids 665 to 686 (22 residues), see Phobius details amino acids 695 to 716 (22 residues), see Phobius details amino acids 723 to 743 (21 residues), see Phobius details PF02421: FeoB_N" amino acids 5 to 163 (159 residues), 213.5 bits, see alignment E=2.8e-67 PF01926: MMR_HSR1" amino acids 5 to 120 (116 residues), 73.2 bits, see alignment E=4.7e-24 TIGR00437: ferrous iron transport protein B" amino acids 10 to 688 (679 residues), 753.5 bits, see alignment E=9.4e-231 PF17910: FeoB_Cyto" amino acids 177 to 259 (83 residues), 41.3 bits, see alignment E=4.4e-14 PF07670: Gate" amino acids 352 to 445 (94 residues), 80.6 bits, see alignment E=2.7e-26 amino acids 513 to 611 (99 residues), 52.3 bits, see alignment E=1.8e-17 PF07664: FeoB_C" amino acids 456 to 508 (53 residues), 78 bits, see alignment 8.9e-26

Best Hits

Swiss-Prot: 76% identical to FEOB_ECOL6: Fe(2+) transporter FeoB (feoB) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K04759, ferrous iron transport protein B (inferred from 78% identity to ctu:CTU_39190)

MetaCyc: 76% identical to Fe2+ transporter FeoB (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-424

Predicted SEED Role

"Ferrous iron transport protein B" in subsystem Campylobacter Iron Metabolism or Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (772 amino acids)

>EX31_RS04850 Fe(2+) transporter permease subunit FeoB (Rahnella sp. WP5)
MKPLTIGLIGNPNSGKTTLFNQLTGSRQRVGNWAGVTVERKEGQFATAAHQITLVDLPGT
YSLTTISEQTSLDEQIACHYILSGDADLMINVVDASNLERNLYLTLQLLELGVPCIVALN
MLDIAKIQNINIDIPALSARLGCPVVALVSTRASGIKELKAAIDELPQVAVLERVQYHPV
LQQEVDVLAAEMPPAMALQQRRWLALQILEGDIYSQTHAGNAQALLPQVRARLAEQKLDD
PALLIADARYQSIAALCAEISNSHLTAPNKLTQVLDRVILNRFLGVPIFLLVMYLMFVLA
INIGGALQPIFDIGSAAIFIQGMQWIGFTLHFPQWLTIFLAQGLGGGINTVLPLVPQIGM
MYLFLSFLEDSGYMARAAFVMDRLMQSLGLPGKSFVPLIVGFGCNVPSIMGARTLDAPRE
RLITVMMAPFMSCGARLAIFAVFSAAFFGQDGASVVFSLYLLGIVVAILTGLLLKYTIMR
GEASPFVMELPVYHVPHLKSLLLQTWQRLKGFVLRAGKVIVIASIFIGALNSFSFSGKAV
DNINDSALASVSKVLTPVLSPMGVHPDNWQATVGLVTGAMAKEVVVGTLNTLYTAEHITN
EAFDAASFNLFDELGGAVKETWQGLKDTFSISVLSNPIEASKGDGEMGVSSMGVMSTKFG
SAISAYSYLIFVLLYVPCVSVMGAIARETSRSWMTFSIFWGLNVAYSLATLFYQAATFST
HPAHSAGIILIVLIFNALVLTALRKARSRVSVHLQPRNVAACCKPATGSDCH