Protein Info for EX31_RS03210 in Rahnella sp. WP5

Annotation: Fe(3+)-hydroxamate ABC transporter permease FhuB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 662 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details transmembrane" amino acids 58 to 79 (22 residues), see Phobius details amino acids 91 to 111 (21 residues), see Phobius details amino acids 117 to 138 (22 residues), see Phobius details amino acids 146 to 171 (26 residues), see Phobius details amino acids 191 to 209 (19 residues), see Phobius details amino acids 222 to 242 (21 residues), see Phobius details amino acids 248 to 266 (19 residues), see Phobius details amino acids 274 to 292 (19 residues), see Phobius details amino acids 303 to 324 (22 residues), see Phobius details amino acids 352 to 371 (20 residues), see Phobius details amino acids 394 to 413 (20 residues), see Phobius details amino acids 425 to 444 (20 residues), see Phobius details amino acids 450 to 470 (21 residues), see Phobius details amino acids 482 to 501 (20 residues), see Phobius details amino acids 521 to 541 (21 residues), see Phobius details amino acids 547 to 565 (19 residues), see Phobius details amino acids 570 to 596 (27 residues), see Phobius details amino acids 609 to 633 (25 residues), see Phobius details amino acids 639 to 657 (19 residues), see Phobius details PF01032: FecCD" amino acids 18 to 324 (307 residues), 225.9 bits, see alignment E=3.3e-71 amino acids 360 to 659 (300 residues), 225.3 bits, see alignment E=4.8e-71

Best Hits

Swiss-Prot: 64% identical to FHUB_ECOLI: Iron(3+)-hydroxamate import system permease protein FhuB (fhuB) from Escherichia coli (strain K12)

KEGG orthology group: K02015, iron complex transport system permease protein (inferred from 100% identity to rah:Rahaq_3654)

MetaCyc: 64% identical to iron(III) hydroxamate ABC transporter membrane subunit (Escherichia coli K-12 substr. MG1655)
ABC-11-RXN [EC: 7.2.2.16]; TRANS-RXN-297 [EC: 7.2.2.16]; TRANS-RXN-298 [EC: 7.2.2.16]

Predicted SEED Role

"Ferric hydroxamate ABC transporter (TC 3.A.1.14.3), permease component FhuB" in subsystem Iron acquisition in Vibrio or Siderophore Aerobactin (TC 3.A.1.14.3)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.2.2.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (662 amino acids)

>EX31_RS03210 Fe(3+)-hydroxamate ABC transporter permease FhuB (Rahnella sp. WP5)
MNRRSFSVSLTLLILLALAAGALSLYNLNQQLPYAQWRGALWQPDIDNVQQMLFHYSLLP
RVAVALLAGAGLGLVGLLFQQVLRNPLAEPATLGVSAGAQLGLTVATLWALPGGMITQQF
AAMAGAVVIGALVFGIAWGKRMSPVTLILAGLVLGLYCGAVNGLIGIFNYQNLQSLYMWS
SGALNQQDWDIANFLLPRVIIVWLLAFLLQRPMTLLGLDDGIAKNLGLGLSAARLAVLTL
AILMSAQLVNAVGIIGFIGLFAPLLAKMLGARRLAARLIIAPVIGALLLWLTDQVMQTLT
TFWMEIPTGAATALVGAPLLLWLLPRLRNNMTPPPMDQGDHVPVERQHLVRWMSLALAVL
LLGLMVALMAGRNATGWSWSTGADLQALLPWRLPRVMAALAAGIMLASSGVLIQKLTGNA
MASPEVLGISSGAATGVVVMMFIVPGDAFVWLLPAGSAGAALTLLVIMVASGLRSFSAER
MLLTGIALSTAFTTLMTLLLASGDPRMGGLLTWLSGSTYSVSAEAAWRTLILAGVLMVLV
PFCRRWINILPLGSVTAKSVGLALTPTRLAILLLAAVMTAAATLTVGPLSFVGLMAPHMA
RMMGFRRAVPQWMVASILGGLLMVFADWCGRMIIFPDQIPAGLLATFIGAPYFIYLLRKQ
AG