Protein Info for EX31_RS03010 in Rahnella sp. WP5

Annotation: helix-turn-helix domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 182 PF13560: HTH_31" amino acids 15 to 61 (47 residues), 42.7 bits, see alignment E=1.2e-14 PF01381: HTH_3" amino acids 15 to 64 (50 residues), 54.5 bits, see alignment E=2e-18 PF13443: HTH_26" amino acids 18 to 68 (51 residues), 31.4 bits, see alignment E=3.7e-11 PF07883: Cupin_2" amino acids 110 to 178 (69 residues), 35.4 bits, see alignment E=1.4e-12

Best Hits

KEGG orthology group: None (inferred from 100% identity to rah:Rahaq_3614)

Predicted SEED Role

"Transcriptional regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (182 amino acids)

>EX31_RS03010 helix-turn-helix domain-containing protein (Rahnella sp. WP5)
MSQPISVISKGLVRERQRAGLSLAEVARRAGIAKSTLSQLEAGNGNPSLETLWALCVALN
IPFARLMEPEVNKMQVIRRGEGPAVVAELADYKAVLLATCPPAARRDIYLLTTQPGADRI
SSPHPQGSVEHIIITQGRALVGLVDSPVELNAGDYISYPADVEHIFRALEPDTMAVLVSE
QS