Protein Info for EX31_RS02785 in Rahnella sp. WP5

Annotation: polysaccharide biosynthesis tyrosine autokinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 716 transmembrane" amino acids 32 to 51 (20 residues), see Phobius details amino acids 425 to 445 (21 residues), see Phobius details PF02706: Wzz" amino acids 16 to 107 (92 residues), 57.8 bits, see alignment E=2.9e-19 PF23607: WZC_N" amino acids 115 to 204 (90 residues), 41.7 bits, see alignment E=3.5e-14 PF13807: GNVR" amino acids 368 to 446 (79 residues), 99.3 bits, see alignment E=2.3e-32 TIGR01007: capsular exopolysaccharide family" amino acids 504 to 704 (201 residues), 144.2 bits, see alignment E=1.9e-46 PF01656: CbiA" amino acids 526 to 696 (171 residues), 29 bits, see alignment E=2.2e-10 PF13614: AAA_31" amino acids 534 to 645 (112 residues), 45.4 bits, see alignment E=2.2e-15

Best Hits

KEGG orthology group: None (inferred from 99% identity to rah:Rahaq_3566)

Predicted SEED Role

"Tyrosine-protein kinase Wzc (EC 2.7.10.2)" in subsystem Colanic acid biosynthesis (EC 2.7.10.2)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.10.2

Use Curated BLAST to search for 2.7.10.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (716 amino acids)

>EX31_RS02785 polysaccharide biosynthesis tyrosine autokinase (Rahnella sp. WP5)
MIGKMTGQSGNKCIPDEFDLRKNMGAIIDKRYIIIVITFIFVFIGLLYAFLSSPVYHADA
LVQVDHSGEIDMMSNISQLLPAKSPVSATEMQLVTSRAILGETVAKLNLDTEVRFISFPI
IGEAIRRYSQPGVPRIAVDIFEPRRGVIGGSYTLEILSDAEYQITSPSGTTVSGMAGKIL
ETPEFRIEVNEIHALKGDKFSVTKVETLKVIEELRANVNVIDQGKDTGILTISYNGKDRK
QIKNILQTIIDCYARQSIHRKAEEAEKSLGFIKSQLPQVKNNLGIAETKLNAFRSRNNSV
DLPMEAKSTLDSMVQLDGQINQLILKETEISKLYTTQHPAYLALIEKIQVLKDEKKNLNE
KVSTLPLTQQEVVRLTRDVQSGQLVYMQLLNKQQELKISQASTIGSVRIIDSAVTGLKPV
KPDKVLIIFIFACLGLISSVGFILAQVSLQQGIDSAEILEDIGLNVVSNVPLSEWRNDHY
SHSMSDTRPVSLLALEKASDIAIEALRNLRTSLYFSMMEARSNVLMISGATPEVGKTFIS
SNLAVVVSQADKRVLYIDCDMRKGYAHRIFDVKNVGLTDAITGSITCQEAVQSTKIPGLD
IITRGKWSKNPSELLLRKQYHDLIHWASDNYDFVILDAPPVLAVSDAVIIGRYAGISMLV
AKFEQSTVREIESAIRVFNRNNIDINGVILNAVVNKPSGFYNYGKKEIYEYHSPET