Protein Info for EX31_RS02650 in Rahnella sp. WP5

Annotation: SprT family zinc-dependent metalloprotease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 173 PF10263: SprT-like" amino acids 19 to 115 (97 residues), 79.6 bits, see alignment E=1.5e-26 PF17283: Zn_ribbon_SprT" amino acids 126 to 164 (39 residues), 37 bits, see alignment 2.9e-13

Best Hits

Swiss-Prot: 77% identical to SPRT_SERP5: Protein SprT (sprT) from Serratia proteamaculans (strain 568)

KEGG orthology group: K02742, SprT protein (inferred from 99% identity to rah:Rahaq_3539)

Predicted SEED Role

"Protein sprT"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (173 amino acids)

>EX31_RS02650 SprT family zinc-dependent metalloprotease (Rahnella sp. WP5)
MKTSRLPIALQQAVMRCLREKLQMANQFFGTDYTEPEISYQQRGTSAGSAYLQHWQIRLN
PVLLLENQQPFIDEVVPHELAHLLVYRRFGRAPAPHGKEWRWMMEHVLGVSASRTHKFEV
ASVQSKTYPYLCACRDHQLTVRRHNKVMRKESEYRCRHCGELLRFNANGITNC