Protein Info for EX31_RS02475 in Rahnella sp. WP5

Annotation: 3-oxoacyl-ACP synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF08541: ACP_syn_III_C
  • amino acids 218 to 305 (88 residues), 62.6 bits, E=1.6e-21

Best Hits

KEGG orthology group: K00648, 3-oxoacyl-[acyl-carrier-protein] synthase III [EC: 2.3.1.180] (inferred from 99% identity to rah:Rahaq_4691)

Predicted SEED Role

"3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.180)" (EC 2.3.1.180)

MetaCyc Pathways

• superpathway of fatty acids biosynthesis (E. coli) (40/53 steps found)
• superpathway of fatty acid biosynthesis I (E. coli) (13/16 steps found)
• superpathway of fatty acid biosynthesis initiation (5/5 steps found)
• fatty acid biosynthesis initiation (type II) (3/3 steps found)
• superpathway of fatty acid biosynthesis II (plant) (30/43 steps found)
• streptorubin B biosynthesis (15/34 steps found)

KEGG Metabolic Maps

• Fatty acid biosynthesis

Isozymes

Compare fitness of predicted isozymes for: 2.3.1.180

Use Curated BLAST to search for 2.3.1.180

Protein Sequence (328 amino acids)

>EX31_RS02475 3-oxoacyl-ACP synthase (Rahnella sp. WP5)
MLGHIESLTVYIPEQRKSLAEVAPALQLSPLDIRMFSRFYGLASFPRQPGSLDDLLRPLL
KQFTDNHADWLPRIKHVVHAHTLPGIRPFDLSGKALLDEAGFADDTHYTSLTMGHCSTSL
SAVEYVCSRIKTGEYALLLVGEKAFHPKVELIDDTTIMGEAACAVLLSRAGERCKVTARY
SMQAGEFSQHRGNESGKESRFASVYFSFIATAMRNALEHFGHTAGSLDWIAPHNVNLSSW
QKLADELNIPRQTLFLENVPRYGHCFGADPYLNLATLIRQKRLSPGNHVMLVSVGMGATF
SSLLLVLSAGNEIPVFCNLEQFPDIKQD