Protein Info for EX31_RS02270 in Rahnella sp. WP5

Annotation: transcriptional regulator ChbR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 278 PF07883: Cupin_2" amino acids 33 to 80 (48 residues), 33.6 bits, see alignment 5e-12 PF02311: AraC_binding" amino acids 38 to 80 (43 residues), 21.6 bits, see alignment 3.1e-08 PF12833: HTH_18" amino acids 198 to 272 (75 residues), 73.5 bits, see alignment E=2.8e-24 PF00165: HTH_AraC" amino acids 235 to 272 (38 residues), 31.5 bits, see alignment 3e-11

Best Hits

Swiss-Prot: 77% identical to CHBR_ECOLI: HTH-type transcriptional regulator ChbR (chbR) from Escherichia coli (strain K12)

KEGG orthology group: K03490, AraC family transcriptional regulator, cel operon repressor (inferred from 100% identity to rah:Rahaq_4650)

Predicted SEED Role

"N,N'-diacetylchitobiose-specific regulator ChbR, AraC family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (278 amino acids)

>EX31_RS02270 transcriptional regulator ChbR (Rahnella sp. WP5)
MQPPVLSMEIKTARENQLFDGQNFHMFIYNKVESISGLHEHDYYEFTVVLTGRYYQNVNG
KRVLLERGDFVFIPLGSHHQSFYEFGATRILNVGISKAFFEQHYLSLLPSRFVASQVYQI
KTEFLAYIESVIASLNFRNGEFNEFLEMVTFYIVNRLRHHRESEITTDAPGWLKNTIEKM
HDKTQFSDKALTNMVALSGKSQEYLSRATQRHYGKTPMQIINEIRIDFAKKQLEITNYSV
TDIAFESGYSSPSMFIKNFKKLTSFTPNHYRKKLCSIN