Protein Info for EX31_RS02085 in Rahnella sp. WP5

Annotation: SDR family oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 246 PF00106: adh_short" amino acids 6 to 184 (179 residues), 156.5 bits, see alignment E=1.3e-49 PF13561: adh_short_C2" amino acids 13 to 245 (233 residues), 193.9 bits, see alignment E=6.8e-61 PF01370: Epimerase" amino acids 17 to 176 (160 residues), 25.8 bits, see alignment E=1.3e-09

Best Hits

Swiss-Prot: 58% identical to FUCDH_XANCP: 2-keto-3-deoxy-L-fuconate dehydrogenase (XCC4067) from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)

KEGG orthology group: None (inferred from 100% identity to rah:Rahaq_4611)

MetaCyc: 64% identical to 2-dehydro-3-deoxy-D-pentonate/2-dehydro-3-deoxy-L-fuconate 4-dehydrogenase (Herbaspirillum huttiense)
RXN-22641 [EC: 1.1.1.434]; 1.1.1.434 [EC: 1.1.1.434]

Predicted SEED Role

"2-keto-3-deoxy-L-fuconate dehydrogenase" in subsystem L-fucose utilization temp

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.1.1.434

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (246 amino acids)

>EX31_RS02085 SDR family oxidoreductase (Rahnella sp. WP5)
MNLAGKKVLITAAGQGIGFNTATLFAREGAEVIATDINIDALHNIPGITPRLLDVTDPQA
IVALAEETGALDVLFNCAGVVHSGDILTCTEREWQFALDLNVTAMFRMIRAFLPAMLERN
HGSVINMSSVASSIKGVPNRFAYSASKAAVIGLTRSVAADYVTRGIRCNAICPGTVESPS
LRQRIAAQAKAEGRSEAEVYAAFVSRQPIGRIGKTEEIAQLALYLASDASSYTTGTVQII
DGGWSN