Protein Info for EX31_RS01705 in Rahnella sp. WP5

Annotation: site-specific DNA-methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 374 PF01555: N6_N4_Mtase" amino acids 22 to 128 (107 residues), 39.4 bits, see alignment E=3.5e-14 amino acids 297 to 360 (64 residues), 60.6 bits, see alignment E=1.1e-20

Best Hits

Predicted SEED Role

"Adenine-specific methyltransferase (EC 2.1.1.72)" (EC 2.1.1.72)

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.72

Use Curated BLAST to search for 2.1.1.72

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (374 amino acids)

>EX31_RS01705 site-specific DNA-methyltransferase (Rahnella sp. WP5)
MSYQLNVGRCEDVLRGVADNSVDSIVTDPPYGLNFMGHKWDYQVPTVEQWAECLRVLKPG
GHLLAFGGSRTYHRLVVNIEDAGFEIRDQLMWIYGSGFPKSKNLQGENAGMGTALKPAHE
PIAMARKPLIGNVETNVEQFGTGALHIDISRVPTEEALTGGAGALLSHVRDDKAPDCAEW
QPGQLGRWPANVIHDGSEEVIAAFPDAKGQQGDLKTTGKSRPARVCYGDMNAPREHAARV
EISRSAARFFYCAKVTKTERDEGMERFVPVTASEMTGGRVEGSAGLNDPRAGAGRTSGAR
NAHPTVKPCDLMRYLCRLITPAGGTVLDPFMGSGSTGKAAILDGFSFIGIELDPDHLTTA
AARIAHSVKVIADE