Protein Info for EX31_RS01030 in Rahnella sp. WP5

Annotation: low affinity potassium transporter Kup

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 624 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details transmembrane" amino acids 47 to 67 (21 residues), see Phobius details amino acids 99 to 121 (23 residues), see Phobius details amino acids 140 to 158 (19 residues), see Phobius details amino acids 170 to 190 (21 residues), see Phobius details amino acids 211 to 234 (24 residues), see Phobius details amino acids 246 to 267 (22 residues), see Phobius details amino acids 287 to 312 (26 residues), see Phobius details amino acids 338 to 358 (21 residues), see Phobius details amino acids 365 to 388 (24 residues), see Phobius details amino acids 395 to 414 (20 residues), see Phobius details amino acids 421 to 441 (21 residues), see Phobius details PF02705: K_trans" amino acids 15 to 545 (531 residues), 712 bits, see alignment E=2.3e-218 TIGR00794: potassium uptake protein" amino acids 102 to 550 (449 residues), 549.2 bits, see alignment E=8e-169

Best Hits

Swiss-Prot: 70% identical to KUP_CROS8: Low affinity potassium transport system protein kup (kup) from Cronobacter sakazakii (strain ATCC BAA-894)

KEGG orthology group: None (inferred from 100% identity to rah:Rahaq_4934)

MetaCyc: 68% identical to K+:H+ symporter Kup (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-3

Predicted SEED Role

"Kup system potassium uptake protein" in subsystem Potassium homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (624 amino acids)

>EX31_RS01030 low affinity potassium transporter Kup (Rahnella sp. WP5)
MKQTKNKSSLLTVTVACIGVVYGDIGTSPLYTLRECLTGQAGITVTQSALFGFLSLIFWL
LMLVVSVKYISFVMRADNDGEGGILTLMALAIRNLNPRWIPCIMFIGLVGGSFFYGDGVI
TPAISVLSAIEGLEIIEPSLDRFIIPFSIAVLTLLFFIQKNGTGSVGKIFAPVMVVWFIT
IGALGIGGIVRNPDVLQALNPYWAVHFFVEFKTVSFFALGMVVLSVTGGEALYADMGHFG
KKPIRIAWFVLVGPSLVMNYFGQGALLLSQPAAIKNPFFLLAPDWALVPLLVLATLATVI
ASQAVISGVFSLTRQAVRMGYLPPMRIIYTSDVESGQIYIPVVNWLLYFAVLIAIVSFKH
SSNLASAYGIVVTGTMVITSVLIGIVMIKNWGWKSWAGGLVITAMLLIDVPLFAANLSKI
FSGGWLPVAIGLTILVIMLTWKTERSRLLRRLRQDPEALEALITSLEKAPPQRVPGTAVV
MSRGQYEVPLVLLHNLKHNKILHERVVLLTIVTEDVPYVHNVQRVIIEQLSPAFWRVIAR
YGWREKPNVTDILYRCGLEGLQSNMNETSFFMSRDTFILGEPRPWYLKARGKLFQVLQRN
SLRAPEHYHIPPNRVIELGAVVKF