Protein Info for EX31_RS00735 in Rahnella sp. WP5

Annotation: mechanosensitive ion channel family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 358 transmembrane" amino acids 15 to 40 (26 residues), see Phobius details amino acids 67 to 88 (22 residues), see Phobius details amino acids 100 to 122 (23 residues), see Phobius details amino acids 135 to 159 (25 residues), see Phobius details amino acids 165 to 187 (23 residues), see Phobius details PF21088: MS_channel_1st" amino acids 144 to 184 (41 residues), 33.8 bits, see alignment 3.9e-12 PF00924: MS_channel_2nd" amino acids 185 to 252 (68 residues), 70 bits, see alignment E=2.2e-23 PF21082: MS_channel_3rd" amino acids 258 to 343 (86 residues), 52.4 bits, see alignment E=8.7e-18

Best Hits

KEGG orthology group: None (inferred from 100% identity to rah:Rahaq_4874)

Predicted SEED Role

"Putative inner membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (358 amino acids)

>EX31_RS00735 mechanosensitive ion channel family protein (Rahnella sp. WP5)
MNFLSRFDFIALVMAPVFWIGVATMCVVTLVTYWLLSWLVSFLRKGVKRWGEVNEASHRI
RFILGEILNRTSNLLIFIAAFLFSLRFVNLPDNLYNTISHAWFLVLAFQMALWLDQAVVS
WLRHIMRQPGMNKNPVTLVITGLIFRAVVWSVMLLSILANVGVNITALVASLGVGGIAIA
LAIQTILSDVFASLSIGFDKPFEIGDFVVFNDVAGTVEHIGLKTTRIRSLSGEQIVCGNA
ILLQQTLHNYKRMQTRRIVFNFGVAINTLPEKLRNIGDMVKEIIIDVGETKFDRAHLLGF
GTDRLNIEVVHIVNTADYNKYMDIQQEINIRIIEKLIEQGIEMALPNMIVKTQAERDR