Protein Info for EX31_RS00670 in Rahnella sp. WP5

Annotation: pyrroloquinoline quinone biosynthesis protein PqqB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 303 signal peptide" amino acids 1 to 16 (16 residues), see Phobius details TIGR02108: coenzyme PQQ biosynthesis protein B" amino acids 2 to 303 (302 residues), 408 bits, see alignment E=1.1e-126 PF12706: Lactamase_B_2" amino acids 51 to 270 (220 residues), 137.7 bits, see alignment E=2e-44

Best Hits

Swiss-Prot: 79% identical to PQQB_ERWT9: Coenzyme PQQ synthesis protein B (pqqB) from Erwinia tasmaniensis (strain DSM 17950 / CIP 109463 / Et1/99)

KEGG orthology group: K06136, pyrroloquinoline quinone biosynthesis protein B (inferred from 99% identity to rah:Rahaq_4860)

Predicted SEED Role

"Coenzyme PQQ synthesis protein B" in subsystem Coenzyme PQQ synthesis or Pyrroloquinoline Quinone biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (303 amino acids)

>EX31_RS00670 pyrroloquinoline quinone biosynthesis protein PqqB (Rahnella sp. WP5)
MQIIVLGSAAGGGFPQWNCNCSNCQGVRNGTMKTSPRTQSSIAVSDNGTDWVLCNASPDI
CHQIAATPELIKHDVLRGTAIGSIILTDSQIDHCTGLLNLREGCPHQVWCTPEVHEDLTT
GFPIFTMLSHWNGGLQHHAIAPEKRFSVAVCPNLTFTAIPLLSNAPPYSKYRGKPLPGHN
IALFIEDTKTGTSLLYAPGLGEPDDELLKWLHKADCLLIDGTLWQDNELATTGVGRNTGK
DMGHLALAEEQGLIALLSSLPAERKILIHINNTNPILNEASAERQALTQQNIEVSWDGMR
IEL