Protein Info for EX31_RS00340 in Rahnella sp. WP5

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 473 transmembrane" amino acids 20 to 43 (24 residues), see Phobius details amino acids 57 to 79 (23 residues), see Phobius details amino acids 87 to 106 (20 residues), see Phobius details amino acids 112 to 133 (22 residues), see Phobius details amino acids 145 to 167 (23 residues), see Phobius details amino acids 175 to 195 (21 residues), see Phobius details amino acids 207 to 225 (19 residues), see Phobius details amino acids 236 to 255 (20 residues), see Phobius details amino acids 275 to 299 (25 residues), see Phobius details amino acids 306 to 326 (21 residues), see Phobius details amino acids 338 to 358 (21 residues), see Phobius details amino acids 365 to 384 (20 residues), see Phobius details amino acids 405 to 430 (26 residues), see Phobius details amino acids 442 to 460 (19 residues), see Phobius details TIGR00711: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family" amino acids 22 to 430 (409 residues), 234.1 bits, see alignment E=1.5e-73 PF07690: MFS_1" amino acids 26 to 418 (393 residues), 163.8 bits, see alignment E=5.6e-52 PF00083: Sugar_tr" amino acids 30 to 192 (163 residues), 31.3 bits, see alignment E=1.1e-11

Best Hits

KEGG orthology group: K08169, MFS transporter, DHA2 family, multidrug resistance protein (inferred from 99% identity to rah:Rahaq_4789)

Predicted SEED Role

"Permeases of the major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (473 amino acids)

>EX31_RS00340 MFS transporter (Rahnella sp. WP5)
MELFSDKPGDEGLPGRERGFAMAAVMIMATMAVFDGSMVNIALPQIAHALDISAGAAVWV
SNGYLLSASMTLAIFAALASRIGFRPLFAAGLTVFTLASLGCALASSLNMLIIMRVLQGI
GAAATLSIGPAILRSVFPNRLLGRILGLNALMIATSTAVAPVLGGTILSAMSWQWLFAIN
IPLGIIAVILTLRVVPSNPASTRQPFDTAGAILSAVALGALIMAAESFAHPGNDKLATAI
TYGLTAIIAGVAFVWRQRRAPKPLLPLGMFASTRFTLAAFTSLASFVSQGITFVALPFLF
QSVYGYSAFVSALLFTPWPLGIILAAPHAGRLADRYPAAIISTVGLAVFAVGLLLLAQLP
AQPQVWDIGLRSFICGLGFGCFQSPNNREMLSNASRENSGYASGVLAIMRTFGQCLGTAC
VGIILTLYSASTVLHEAQAVKVSLWVAVMATVLASVISLSRLRGQRGHLQAEK