Protein Info for EX31_RS00245 in Rahnella sp. WP5

Annotation: HTH-type transcriptional activator RhaS

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 274 PF02311: AraC_binding" amino acids 18 to 155 (138 residues), 53.7 bits, see alignment E=3.8e-18 PF00165: HTH_AraC" amino acids 181 to 222 (42 residues), 29.2 bits, see alignment 1.6e-10 amino acids 237 to 272 (36 residues), 39.6 bits, see alignment 8.6e-14 PF12833: HTH_18" amino acids 194 to 272 (79 residues), 83.3 bits, see alignment E=2.5e-27

Best Hits

Swiss-Prot: 58% identical to RHAS_SALSV: HTH-type transcriptional activator RhaS (rhaS) from Salmonella schwarzengrund (strain CVM19633)

KEGG orthology group: K02855, AraC family transcriptional regulator, L-rhamnose operon regulatory protein RhaS (inferred from 100% identity to rah:Rahaq_4769)

Predicted SEED Role

"L-rhamnose operon regulatory protein RhaS" in subsystem L-rhamnose utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (274 amino acids)

>EX31_RS00245 HTH-type transcriptional activator RhaS (Rahnella sp. WP5)
MTVLRSSEYFPSGDFPVAIEPRYPQETFPEHHHQDFNEIVLVEQGTGTHVFNDQPLILSA
GSVCFVRHSDHHLYEDTENLHLTNVLYRSPNAFRFLNGVGDLLPQEVDGVYPAHWRISPT
QIVQAKTLINLLARQPAMQSPESQAQQELYFMQLLLLLRKGSRDVGYRGQGGDLNNVLDW
MNEHYDEEIDWPALAAQFSMSLRTLHRQMKQQTGCTPLNYLNRLRLLNARNMLRFSDSPI
TEIAHNCGFCDSNYFSTLFKREFGYAPRSVRQYQ