Protein Info for EX31_RS00235 in Rahnella sp. WP5

Annotation: sugar ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 504 PF00005: ABC_tran" amino acids 24 to 175 (152 residues), 109.2 bits, see alignment E=2.6e-35 amino acids 276 to 428 (153 residues), 89.6 bits, see alignment E=3e-29

Best Hits

Swiss-Prot: 59% identical to RBSA1_RHIME: Ribose import ATP-binding protein RbsA 1 (rbsA1) from Rhizobium meliloti (strain 1021)

KEGG orthology group: K10562, rhamnose transport system ATP-binding protein [EC: 3.6.3.17] (inferred from 100% identity to rah:Rahaq_4767)

Predicted SEED Role

"Predicted L-rhamnose ABC transporter, ATP-binding component" in subsystem L-rhamnose utilization

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.17

Use Curated BLAST to search for 3.6.3.17

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (504 amino acids)

>EX31_RS00235 sugar ABC transporter ATP-binding protein (Rahnella sp. WP5)
MSDSATPLLSLKGISKVFPGVRALNNVHVDLYPGKVTALIGENGAGKSTLVKVMTGIYQP
EEGELHYKAIPIKLPNPESAHKIGITAIHQETVLFDELSVTENIFVGHYLYRGIFKRLNW
PAMHQQARDILTRLEVNIDPHAILKELSIAQRHMVAIARALSFDAQVVILDEPTAALSQH
EIVEFYQIVERLKQEGKAILFISHKFDEIFSISDYYTVLRDGSYVGSGKISDISEQQMVT
MMVGREVSQAYPKVNCEPGDTVLEVQNLSHPTEFAGINFSLRKGEILGFYGLVGAGRTEL
MQALFGVTQPNGGKILINGKEHHFSRPSQAIRAGIVYVPEERQKQGAIIDLPISQNISLP
QLSQLNPRGVLNDKKEWALADDYARRLQVKASSWKQAVGTLSGGNQQKVVIAKWLATKPD
IIILDEPTKGIDIGSKAAVHQFMSELVGRGLAVIMVSSELPEVMGMADRIIVMHEGLMVA
EFNAGEASAEMIVSAASGAGEEAA