Protein Info for ECOLIN_RS25550 in Escherichia coli Nissle 1917

Annotation: type II CAAX endopeptidase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 228 transmembrane" amino acids 16 to 36 (21 residues), see Phobius details amino acids 47 to 67 (21 residues), see Phobius details amino acids 79 to 102 (24 residues), see Phobius details amino acids 115 to 136 (22 residues), see Phobius details amino acids 156 to 172 (17 residues), see Phobius details amino acids 178 to 196 (19 residues), see Phobius details amino acids 202 to 223 (22 residues), see Phobius details PF02517: Rce1-like" amino acids 122 to 214 (93 residues), 61.8 bits, see alignment E=3.1e-21

Best Hits

KEGG orthology group: K07052, (no description) (inferred from 100% identity to ecc:c1233)

Predicted SEED Role

"FIG00510943: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (228 amino acids)

>ECOLIN_RS25550 type II CAAX endopeptidase family protein (Escherichia coli Nissle 1917)
MEMTKNKNATIKKQSSAGCFSMFTLSFSITFIPAFLTNRQELISRGLLVPALFLAEFLIL
VPLYFIFFRKREGLGRGSFRLDVFFTLFSLIMIIQLFVPYLLAVRKTEEWMISQMSFSGA
ILWINIFSSVLLVPVYEEIVFRGCLFNSFKFWFNDNIYTSAIVTSVIFSALHLQYTDFHT
FLMLFLVSLVLISAKIKSNGLLMPILLHMSMNAVIAGIQYLASISYTH