Protein Info for ECOLIN_RS24460 in Escherichia coli Nissle 1917

Annotation: DMT family transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 321 transmembrane" amino acids 5 to 25 (21 residues), see Phobius details amino acids 35 to 52 (18 residues), see Phobius details amino acids 64 to 86 (23 residues), see Phobius details amino acids 92 to 113 (22 residues), see Phobius details amino acids 125 to 142 (18 residues), see Phobius details amino acids 154 to 175 (22 residues), see Phobius details amino acids 195 to 216 (22 residues), see Phobius details amino acids 231 to 253 (23 residues), see Phobius details amino acids 262 to 281 (20 residues), see Phobius details amino acids 288 to 306 (19 residues), see Phobius details PF00892: EamA" amino acids 3 to 126 (124 residues), 56.3 bits, see alignment E=2.1e-19

Best Hits

Swiss-Prot: 99% identical to YTFF_ECOLI: Inner membrane protein YtfF (ytfF) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 99% identity to eco:b4210)

Predicted SEED Role

"Putative membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (321 amino acids)

>ECOLIN_RS24460 DMT family transporter (Escherichia coli Nissle 1917)
MISGVLYALLAGLMWGLIFVGPLIVPEYPAMLQSMGRYLALGLIALPIAWLGRVRLRQLA
RRDWLTALMLTMMGNLIYYFCLASAIQRTGAPVSTMIIGTLPVVIPVFANLLYSQRDGKL
AWGKLAPALVCIGIGLACVNIAELNHGLPDFDWARYTSGIVLALVSVVCWAWYALRNARW
LRENPDKHPMMWATAQALVTLPVSLIGYLVACYWLNMQTPDFSLPFGPRPLVFISLMVAI
AVLCSWVGALCWNVASQRLPTVILGPLIVFETLAGLLYTFLLRQQMPPLMTLSGIALLVI
GVVIAVRAKPEKPLTESVSES