Protein Info for ECOLIN_RS22570 in Escherichia coli Nissle 1917

Annotation: CDP-diacylglycerol diphosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00672: CDP-diacylglycerol diphosphatase
  • amino acids 1 to 251 (251 residues), 535.7 bits, E=8e-166
• PF02611: CDH
  • amino acids 31 to 249 (219 residues), 309.1 bits, E=9e-97

Best Hits

Swiss-Prot: 100% identical to CDH_ECO27: CDP-diacylglycerol pyrophosphatase (cdh) from Escherichia coli O127:H6 (strain E2348/69 / EPEC)

KEGG orthology group: K01521, CDP-diacylglycerol pyrophosphatase [EC: 3.6.1.26] (inferred from 100% identity to ecz:ECS88_4368)

MetaCyc: 97% identical to CDP-diacylglycerol diphosphatase (Escherichia coli K-12 substr. MG1655)
CDP-diacylglycerol diphosphatase. [EC: 3.6.1.26]

Predicted SEED Role

"CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26)" in subsystem Glycerolipid and Glycerophospholipid Metabolism in Bacteria (EC 3.6.1.26)

KEGG Metabolic Maps

• Glycerophospholipid metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.1.26

Protein Sequence (251 amino acids)

>ECOLIN_RS22570 CDP-diacylglycerol diphosphatase (Escherichia coli Nissle 1917)
MKKAGLLFLVMIVIAVVAAGIGYWKLTGEESDTLRKIVLEQCLPNQQENQNPSPCAEVKP
NAGYVVLKDRHGPLQYLLMPTYRINGTESPLLTDPSTPNFFWLAWQARDFMSQKYGQPVP
DRAVSLAINSRTGRTQNHFHIHISCIRPDVREQLDNNLANISSRWLPLPGGLRGHEYLAR
RVTESELVQRSPFMMLAEEVPEAREHMGSYGLAMVRQSDNSFVLLATQRNLLTLNRASAE
EIQDHQCEILR