Protein Info for ECOLIN_RS22510 in Escherichia coli Nissle 1917

Annotation: L-rhamnose/proton symporter RhaT

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 344 transmembrane" amino acids 6 to 26 (21 residues), see Phobius details amino acids 38 to 58 (21 residues), see Phobius details amino acids 64 to 85 (22 residues), see Phobius details amino acids 97 to 121 (25 residues), see Phobius details amino acids 136 to 154 (19 residues), see Phobius details amino acids 175 to 194 (20 residues), see Phobius details amino acids 214 to 234 (21 residues), see Phobius details amino acids 255 to 277 (23 residues), see Phobius details amino acids 290 to 310 (21 residues), see Phobius details amino acids 322 to 342 (21 residues), see Phobius details PF06379: RhaT" amino acids 1 to 343 (343 residues), 722.5 bits, see alignment E=4.1e-222 TIGR00776: RhaT L-rhamnose-proton symporter family protein" amino acids 7 to 342 (336 residues), 379.9 bits, see alignment E=3.6e-118

Best Hits

Swiss-Prot: 100% identical to RHAT_ECOL5: L-rhamnose-proton symporter (rhaT) from Escherichia coli O6:K15:H31 (strain 536 / UPEC)

KEGG orthology group: K02856, L-rhamnose-H+ transport protein (inferred from 99% identity to eco:b3907)

MetaCyc: 99% identical to rhamnose/lyxose:H+ symporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-112; TRANS-RXN0-236

Predicted SEED Role

"L-rhamnose-proton symporter" in subsystem L-rhamnose utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (344 amino acids)

>ECOLIN_RS22510 L-rhamnose/proton symporter RhaT (Escherichia coli Nissle 1917)
MSNAITMGIFWHLIGAASAACFYAPFKKVKKWSWETMWSVGGIVSWIILPWAISALLLPN
FWAYYSSFSLSTLLPVFLFGAMWGIGNINYGLTMRYLGMSMGIGIAIGITLIVGTLMTPI
INGNFDVLINTEGGRMTLLGVLVALIGVGIVTRAGQLKERKMGIKAEEFNLKKGLVLAVM
CGIFSAGMSFAMNAAKPMHEAAAALGVDPLYVALPSYVVIMGGGAIINLGFCFIRLAKVK
DLSLKADFSLAKPLIIHNVLLSALGGLMWYLQFFFYAWGHARIPAQYDYISWMLHMSFYV
LCGGIVGLVLKEWNNAGRRPVTVLSLGCVVIIVAANIVGIGMAN