Protein Info for ECOLIN_RS13875 in Escherichia coli Nissle 1917

Annotation: phosphocarrier protein Hpr

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 25 50 85 TIGR01003: phosphocarrier, HPr family" amino acids 1 to 82 (82 residues), 105.4 bits, see alignment E=5.8e-35 PF00381: PTS-HPr" amino acids 3 to 82 (80 residues), 104.2 bits, see alignment E=1.6e-34

Best Hits

Swiss-Prot: 100% identical to PTHP_SHIFL: Phosphocarrier protein HPr (ptsH) from Shigella flexneri

KEGG orthology group: K02784, phosphocarrier protein HPr (inferred from 100% identity to eco:b2415)

MetaCyc: 100% identical to phosphocarrier protein HPr (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (85 amino acids)

>ECOLIN_RS13875 phosphocarrier protein Hpr (Escherichia coli Nissle 1917)
MFQQEVTITAPNGLHTRPAAQFVKEAKGFTSEITVTSNGKSASAKSLFKLQTLGLTQGTV
VTISAEGEDEQKAVEHLVKLMAELE