Protein Info for ECOLIN_RS13575 in Escherichia coli Nissle 1917

Annotation: formate/nitrite transporter family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 310 transmembrane" amino acids 58 to 79 (22 residues), see Phobius details amino acids 90 to 108 (19 residues), see Phobius details amino acids 135 to 158 (24 residues), see Phobius details amino acids 187 to 206 (20 residues), see Phobius details amino acids 213 to 240 (28 residues), see Phobius details amino acids 253 to 275 (23 residues), see Phobius details PF01226: Form_Nir_trans" amino acids 40 to 277 (238 residues), 167 bits, see alignment E=2.6e-53

Best Hits

Swiss-Prot: 98% identical to YFDC_ECOLI: Inner membrane protein YfdC (yfdC) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 98% identity to ecl:EcolC_1306)

Predicted SEED Role

"putative transport"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (310 amino acids)

>ECOLIN_RS13575 formate/nitrite transporter family protein (Escherichia coli Nissle 1917)
MDNDKIDQHSDEIEVESEEKERGKKIEIDEDRLPSRAMAIHEHIRQDGEKELERDAMALL
WSAIAAGLSMGASLLAKGIFHVELEGVPGSFLLENLGYTFGFIIVIMARQQLFTENTVTA
VLPVMQKPTMSNVGLLMRLWGIVLLGNIIGTGIAAWAFEYMPIFNEETRDAFVKIGMDVM
KNTPSEMFANAIISGWLIATMVWMFPAAGAAKIVVIILMTWLIALGDTTHIVVGSVEILY
LVFNGTLHWSDFIWPFALPTLAGNICGGTFIFALMSHAQIRNDMSNKRKVEARQKAERAE
NIKKNDKNPA