Protein Info for ECOLIN_RS07895 in Escherichia coli Nissle 1917

Annotation: zinc-binding alcohol dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 PF00107: ADH_zinc_N" amino acids 168 to 289 (122 residues), 89.7 bits, see alignment E=7.9e-30

Best Hits

Swiss-Prot: 98% identical to YCJQ_ECOLI: Uncharacterized zinc-type alcohol dehydrogenase-like protein YcjQ (ycjQ) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to ecc:c1785)

MetaCyc: 98% identical to D-guloside 3-dehydrogenase (Escherichia coli K-12 substr. MG1655)
1.1.1.-

Predicted SEED Role

"Zinc-type alcohol dehydrogenase YcjQ" in subsystem Maltose and Maltodextrin Utilization

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (350 amino acids)

>ECOLIN_RS07895 zinc-binding alcohol dehydrogenase (Escherichia coli Nissle 1917)
MKKLVATAPRVAALVEYEDRAISANEVKIRVRFGAPKHGTEVVDFRAASPFINDDFNGEW
QMFTPRPADAPRGIEFGKFQLGNMVVGDIIECGSDVNDYAVGDSVCGYGPLSETVIINAV
NNYKLRKMPQGSSWKNAVCYDPAQFAMSGVRDANVRVGDFVVVVGLGAIGQIAIQLAKRA
GASVVIGVDPITRRCDIARRHGADFCLNPIGADVGKEIKTLTGKQGADVIIETSGYADAL
QSALRGLAYGGTISYVAFAKPFAEGFNLGREAHFNNAKIVFSRACSEPNPDYPRWSRKRI
EETCWELLMNGYLNCEDLIDPVVTFANSPESYMQYVDQHPEQSIKMGVTF