Protein Info for ECOLIN_RS05820 in Escherichia coli Nissle 1917

Annotation: GTP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 399 PF02492: cobW" amino acids 5 to 203 (199 residues), 96.1 bits, see alignment E=2e-31 PF07683: CobW_C" amino acids 253 to 371 (119 residues), 56.5 bits, see alignment E=2e-19

Best Hits

KEGG orthology group: None (inferred from 100% identity to ecp:ECP_0316)

Predicted SEED Role

"Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (399 amino acids)

>ECOLIN_RS05820 GTP-binding protein (Escherichia coli Nissle 1917)
MNRIPVIIINGFLGAGKTTLMKNLLTQANRNHLAVSVIVNDMSDLDVDGVLIANTEIVNI
ANNNFVSITSDSISSQSGIKTVDKAIKNMLRHYLPDVIFVETSGGSHPLPLIKYLQTHER
LQLKSLLSLVDTVMLNDDYNGGKALIPAFQENLFHGKRRIENLLAEQIMFCSTLLLTKKD
RLSFDIVTDVAKAIHPLNPYVNVIAVSWGNLKLAELLTLPDYDFNRVGLLIRELEDTITV
EEAKISAQNGEIISRVIKDDRPFHPQRLWETYHYFMGMGIYRSKGFFWLPGRPDMALLWN
QAAGSINLEFISYWNSGVLADPDNHLTHEERSVLQKKVNKTMGRFGDRRCHLTIIGRSDE
VHDFTSALINCFLSEEEIVWWQSGGVFADPWPVNISRLN