Protein Info for ECOLIN_RS05755 in Escherichia coli Nissle 1917

Annotation: salmochelin/enterobactin export ABC transporter IroC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1219 transmembrane" amino acids 27 to 48 (22 residues), see Phobius details amino acids 64 to 84 (21 residues), see Phobius details amino acids 137 to 161 (25 residues), see Phobius details amino acids 165 to 184 (20 residues), see Phobius details amino acids 248 to 271 (24 residues), see Phobius details amino acids 283 to 306 (24 residues), see Phobius details amino acids 645 to 670 (26 residues), see Phobius details amino acids 683 to 704 (22 residues), see Phobius details amino acids 763 to 782 (20 residues), see Phobius details amino acids 788 to 806 (19 residues), see Phobius details amino acids 869 to 890 (22 residues), see Phobius details amino acids 896 to 916 (21 residues), see Phobius details PF00664: ABC_membrane" amino acids 30 to 296 (267 residues), 107.1 bits, see alignment E=6.9e-34 amino acids 650 to 919 (270 residues), 136.1 bits, see alignment E=9.5e-43 PF00005: ABC_tran" amino acids 358 to 510 (153 residues), 110.4 bits, see alignment E=5.8e-35 amino acids 980 to 1129 (150 residues), 100.9 bits, see alignment E=5.1e-32

Best Hits

KEGG orthology group: K06148, ATP-binding cassette, subfamily C, bacterial (inferred from 100% identity to ecc:c1253)

Predicted SEED Role

"ABC transporter protein IroC"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1219 amino acids)

>ECOLIN_RS05755 salmochelin/enterobactin export ABC transporter IroC (Escherichia coli Nissle 1917)
MPANHTPTPAQSWIVRLARVCWERKKLSVIVVVASVSTILLAALTPLLTRQAVNDALAGN
PARLPWLACGLLLIAFFDFIGNYVRRGYAGMLSLWVQHTLRGRVFDSIQKLDGAGQDALR
TGQVISRTNSDLQQVHTLLQMCPVPLAVFTYYIAGIAVMLWMSPAMTLIVVCVLVCLAIT
ALRARRRVFAQTGMASDQLANLTEHIREVLAQISVVKSCVAEMRETHWLDRQSRQIVRVR
IGAVISQAMPGATMLALPVLGQIVLLCYGGWSVMHGRIDLGTFVAFASFLAMLTGPTRVL
ASFLVIAQRTQASVERVFALIDTRSQMEDGTESINSQVVGLELENMSFDYHHGDRHILSD
ISFSLRAGETVAVVGASGSGKSTLLMLLARFYDPCSGKIWLNTSEGRQNLRDIRLEALRR
RVGIVFEDAFLFAGTVAENIAYGHPQATADDIRRAAAAAGASDFINALPKGFDSLLTERG
TNLSGGQRQRIALARALITAPDVLILDDTTSAVDAVTEAEINTALGRYADEGHMLLVIAR
RRSTLQLASRVVVLDKGRMVDTGTPAELEARCPAFRALMTGDSDFLATSHNSHNELWPAE
PATQDDVTDTGDKGFVARMTRVPENAVQQALAGKGRKVTSLLKPVAWMFVIAALLIALDS
AAGVGVLILLQHGIDSGVAAGDMSTIGLCALLALCLVIVGWCSYSLQTVFAARAAESVQH
SVRLRSFGHMLRLGLPWHEKHADSRLTRMTVDVDSLARFLQNGLAGAATSLVTMFAIAAT
MFWLDPILALTALSAVPVAALATMIYRRLSTPAYAQARLEIGKVNSTLQEKVSGLRVVQS
HGQQELEGARLRALSERFRATRVRAQKYLAVYFPFLTFCTEASYAAVLLVGASQVAAGEM
TAGVLAAFFLLLGQFYGPVQQLSGIVDAWQQATASGKHIDELLATEGTENLGSSSVLPVT
GALHLDEVTFSYPDSHEPALNKLTLTIPEGMVVAVVGRSGAGKSTLIKLIAGLYFPTHGN
IRIGVQMLDDASLTEYRRQIGLVDQDVALFSSDIAENIRYSRPSATNEDVEIASQRAGLY
EMVCNLPQGFRTPVNNGGADLSAGQRQLIALARAQLANAHILLLDEATSCLDRTSEERLM
SSLTDVVHAGKHSALIVAHRLTTAQRCDLIAVIDKGLLAEYGTHEQLLSAGGLYTRLWHD
SVSSTALHRQHNMKEETPG