Protein Info for ECOLIN_RS01900 in Escherichia coli Nissle 1917

Annotation: fimbrial usher EcpC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 841 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details PF16967: TcfC" amino acids 283 to 350 (68 residues), 91.6 bits, see alignment E=1.7e-30 PF15976: CooC_C" amino acids 732 to 824 (93 residues), 107.4 bits, see alignment E=3.2e-35

Best Hits

Swiss-Prot: 100% identical to ECPC_ECOL6: Probable outer membrane usher protein EcpC (ecpC) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: None (inferred from 100% identity to ecc:c0402)

Predicted SEED Role

"CFA/I fimbrial subunit C usher protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (841 amino acids)

>ECOLIN_RS01900 fimbrial usher EcpC (Escherichia coli Nissle 1917)
MPLRRFSPGLKAQFAFGMVFLFVQPDASAADISAQQIGGVIIPQAFSQALQDGMSVPLYI
HLAGSQGRQDDQRIGSAFIWLDDGQLRIRKIQLEESEDNASVSEQTRQQLTTLANAPFNE
ALTIPLTDNAQLDLSLRQLLLQLVVKREALGTVLRSRSEDIGQSSVNTLSSNLSYNFGVY
NNQLRNGGSNTSSYLSLNNVTALREHHVVLDGSLYGIGSGQQDSELYKAMYERDFAGHRF
AGGMLDTWNLQSLGPMTAISAGKIYGLSWGNQASSTIFDSSQSATPVIAFLPAAGEVHLT
RDGRLLSVQNFTMGNHEVDTRGLPYGIYDVEVEVIVNGRVISKRTQRVNKLFSRGRGVGA
PLAWQIWGGSFHMDRWSENGKKTRPAKESWLAGASTSGSLSTFSWAATGYGYDNQAVGET
RLTLPLGGAINVNLQNMLASDSSWSNIAGISATLPGGFSSLWVNQEKTRIGNQLRRSDAD
NRAIGGTLNLNSLWSKLGTFSISYNDDRRYNSHYYTADYYQSVYSGTFGSLGLRAGIQRY
NNGDSSANTGKYIALDLSLPLGNWFSAGMTHQNGYTMANLSARKQFDEGTIRTVGANLSR
AISGDTGDDKTLSGGAYAQFDARYASGTLNVNSAADGYINTNLTANGSVGWQGKNIAASG
RTDGNAGVIFDTGLENDGQISAKINGRIFPLNGKRNYLPLSPYGRYEVELQNSKNSLDSY
DIVSGRKSHLTLYPGNVAVIEPEVKQMVTVSGRIRAEDGTLLANARINNHIGRTRTDENG
EFVMDVDKKYPTIDFRYSGNKTCEVALELNQARGAVWVGDVVCSGLSSWAAVTQTGEENE
S