Protein Info for ECOLIN_RS00405 in Escherichia coli Nissle 1917
Annotation: leu operon leader peptide
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 100% identical to LPL_SHIFL: leu operon leader peptide (leuL) from Shigella flexneri
KEGG orthology group: K05806, leu operon leader peptide (inferred from 100% identity to eco:b0075)Predicted SEED Role
"Leu operon leader peptide" in subsystem Leucine Biosynthesis
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (28 amino acids)
>ECOLIN_RS00405 leu operon leader peptide (Escherichia coli Nissle 1917) MTHIVRFIGLLLLNASSLRGRRVSGIQH