Protein Info for Dsui_3525 in Dechlorosoma suillum PS

Annotation: CDP-diacylglycerol--serine O-phosphatidyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01066: CDP-OH_P_transf
  • amino acids 22 to 178 (157 residues), 72.9 bits, E=2e-24
• TIGR00473: CDP-diacylglycerol-serine O-phosphatidyltransferase
  • amino acids 30 to 190 (161 residues), 108.9 bits, E=1.2e-35

Best Hits

KEGG orthology group: K00998, phosphatidylserine synthase [EC: 2.7.8.8] (inferred from 78% identity to dar:Daro_3072)

Predicted SEED Role

"CDP-diacylglycerol--serine O-phosphatidyltransferase (EC 2.7.8.8)" in subsystem Glycerolipid and Glycerophospholipid Metabolism in Bacteria (EC 2.7.8.8)

MetaCyc Pathways

• superpathway of phospholipid biosynthesis III (E. coli) (10/12 steps found)
• phosphatidylserine and phosphatidylethanolamine biosynthesis I (2/2 steps found)
• cardiolipin and phosphatidylethanolamine biosynthesis (Xanthomonas) (3/4 steps found)
• superpathway of cardiolipin biosynthesis (bacteria) (9/13 steps found)
• superpathway of phospholipid biosynthesis II (plants) (10/28 steps found)

KEGG Metabolic Maps

• Glycerophospholipid metabolism
• Glycine, serine and threonine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.8.8

Sequence Analysis Tools

See G8QM06 at UniProt or InterPro

Protein Sequence (254 amino acids)

>Dsui_3525 CDP-diacylglycerol--serine O-phosphatidyltransferase (Dechlorosoma suillum PS)
MSELKPRKVLFNPELKRRGIYVLPNLFTTAALFAGFFAIVQAMNGFYEQSAVAIFVAMVL
DGLDGRVARLTHTQSAFGAEYDSLSDMVSFGAAPSLVIYEWALRGMGKLGWIAAFIYCAG
AALRLARFNTTLEVIDKRFFQGLPSPAAAALVAGFVWLMLDNDIVGSDVRVIACILTIFA
GVSMVTNCRFYSFKDINLRKSVPFIFVGAIVLAFALVFMYPPGVLFGLFVVYALSGYALS
GLRLLRRKPASTPL