Protein Info for Dsui_3521 in Dechlorosoma suillum PS

Annotation: membrane-fusion protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 383 signal peptide" amino acids 1 to 42 (42 residues), see Phobius details TIGR01730: efflux transporter, RND family, MFP subunit" amino acids 92 to 376 (285 residues), 164.6 bits, see alignment E=1.5e-52 PF25973: BSH_CzcB" amino acids 93 to 231 (139 residues), 36.8 bits, see alignment E=5.8e-13 PF25954: Beta-barrel_RND_2" amino acids 235 to 306 (72 residues), 68.3 bits, see alignment E=1.1e-22 PF25967: RND-MFP_C" amino acids 326 to 372 (47 residues), 22.8 bits, see alignment 1.5e-08

Best Hits

KEGG orthology group: None (inferred from 48% identity to mep:MPQ_1253)

Predicted SEED Role

"Probable Co/Zn/Cd efflux system membrane fusion protein" in subsystem Cobalt-zinc-cadmium resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QM02 at UniProt or InterPro

Protein Sequence (383 amino acids)

>Dsui_3521 membrane-fusion protein (Dechlorosoma suillum PS)
MKPLKHSPLLQKKVLLPLGIAGALAVAAVLVLRPAAPPAGLAPLAKPALNTNHSISFPPG
APQLAYLRIEAAPELPVPLLEPLAGRVSYDENRTARIFAPTSGRVLKVLAQAGDTVKAGA
PLLTLDVPDYADLRKAESDRETKRSALERSKALYELEVVARKDLEASQNDYRAAEAEVER
SRARLRNLSPLAGESGFALRTPLAGIVTERQASPGVEVRPDGAAPLFVVSDPRSLWVMAE
LTEKDLGKLKVGQAVSIAVDAYPEQRFPGTVEAIGDVLDPQSRRVPVRCAVANPERHLKP
EMFARIVPENPDRRLPKVPNTALVTEGLHTYLFVESEPGVVARREVVLAFRGHDASFVES
GLKAGERVVTAGALLLNAELAGN