Protein Info for Dsui_3485 in Dechlorosoma suillum PS

Annotation: signal transduction histidine kinase regulating C4-dicarboxylate transport system

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 626 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details transmembrane" amino acids 310 to 328 (19 residues), see Phobius details PF02743: dCache_1" amino acids 48 to 295 (248 residues), 49.4 bits, see alignment E=6.9e-17 PF00512: HisKA" amino acids 400 to 466 (67 residues), 34.4 bits, see alignment E=2.9e-12 PF02518: HATPase_c" amino acids 510 to 618 (109 residues), 78.7 bits, see alignment E=6.7e-26

Best Hits

KEGG orthology group: K10125, two-component system, NtrC family, C4-dicarboxylate transport sensor histidine kinase DctB [EC: 2.7.13.3] (inferred from 82% identity to rfr:Rfer_3454)

Predicted SEED Role

"Signal transduction histidine kinase regulating C4-dicarboxylate transport system (EC 2.7.13.3)" (EC 2.7.13.3)

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3

Use Curated BLAST to search for 2.7.13.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QLA0 at UniProt or InterPro

Protein Sequence (626 amino acids)

>Dsui_3485 signal transduction histidine kinase regulating C4-dicarboxylate transport system (Dechlorosoma suillum PS)
MPPSQRLFRLAILLLGFAALAGGTSLLAFRFSLAMGLAELQATGRHRLDLYATSLEREID
KYAYFPTTLGLEKDVLHLLTTPKPTPAQIEQLNLYLEQLNERAGTLSIYVLNVNGRVMAT
SNWRRPDSYLGEDLSFRPYFRQAMDTGSGRFFGIGTTRGEPGYYLTSALTNAQGTVGVAV
LKVGLQQLEKTWSTVEAPALVADENGVVILASVPDWKFTTLKPLDDATRRAFDQTQQYNR
RALNPLGVVELAELDHGARLVRLPKAGPEMVSMFPVAGKFLAQTQPLPGTPWTITVFSHQ
EQVREIAANRAALAGIGAAFLCILALMFNERRRHVRDRLAAREALQKAHDELERKVEERT
ADLSAANTRLQEEVAERTRAERTLRAAQDELVQAGKLAVLGQLSAGVAHELNQPLAALRT
LSGNARKFLARGDQETAGSNLERIGELVDRMGRLTGQLKSFARKSTGKPQAVPIRRAVEN
ALFLLEQRLQRAGVVACIDLPEEELLAWCDPNRLEQVLVNLAANSLDAMAGRPQQALDIS
ARRQGERIEVKVRDQGPGLDEEARSHLFEPFFTTKEAGSGLGLGLAISAGIVADFGGNLT
GDNHPDGGAVFTLDLPAAPAAPGTLS