Protein Info for Dsui_3441 in Dechlorosoma suillum PS

Annotation: cation/multidrug efflux pump

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1083 signal peptide" amino acids 1 to 37 (37 residues), see Phobius details transmembrane" amino acids 365 to 384 (20 residues), see Phobius details amino acids 390 to 411 (22 residues), see Phobius details amino acids 417 to 437 (21 residues), see Phobius details amino acids 467 to 489 (23 residues), see Phobius details amino acids 499 to 519 (21 residues), see Phobius details amino acids 563 to 585 (23 residues), see Phobius details amino acids 928 to 946 (19 residues), see Phobius details amino acids 953 to 973 (21 residues), see Phobius details amino acids 979 to 1002 (24 residues), see Phobius details amino acids 1022 to 1043 (22 residues), see Phobius details amino acids 1050 to 1076 (27 residues), see Phobius details PF00873: ACR_tran" amino acids 17 to 861 (845 residues), 392.4 bits, see alignment E=4e-121 amino acids 907 to 1075 (169 residues), 113.4 bits, see alignment E=7.9e-37 PF02355: SecD_SecF" amino acids 352 to 514 (163 residues), 22.2 bits, see alignment E=8.7e-09 amino acids 925 to 1069 (145 residues), 21.8 bits, see alignment E=1.1e-08

Best Hits

KEGG orthology group: None (inferred from 72% identity to eba:ebA3873)

Predicted SEED Role

"Acriflavin resistance protein" in subsystem Multidrug Resistance Efflux Pumps

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QKN1 at UniProt or InterPro

Protein Sequence (1083 amino acids)

>Dsui_3441 cation/multidrug efflux pump (Dechlorosoma suillum PS)
MGISGRIAHTFQASPMTPLLALVLLLLGLFAVMVTPREEEPQIDVTMANVVVPFPGASSK
DVENLVATPGEQVLSRMTGVDHVFSVSRPGMAVITVQFEVGVKNQDALVRLYDTVHSNRD
WLPANLGVGEPIVKPKGIDDVPIVSLTFWTRDSRRSAFELQQIARSAEVEFKHLAGTRDV
TTLGGPDHVIRVAMDAERMNAYGVTAQDLRDALQIANNEQPSGRLVEGGREMLVHTGTLI
ESAQDVKNLVVAVRSEGSIRKPVFLADVATVEDGPDQPKRYVWFGAGPAAAQRGIAAGGE
DASPDGTYPAVTLAISKKPGVNAADVADAVIARAESLKGSLIPEGVEVTVTRNYGATATE
KAQKLIGKLVFATAFVVLLVFFALGRREALIVGIAVSLTLAATLFASWAWGFTLNRVSLF
ALIFSIGILVDDAIVVVENIHRWKLLHPEKTLLELIPGAVDEVGGPTILATLTVIAALLP
MAFVTGLMGPYMSPIPINSSLGMAISLAVAFIVTPWLAAKLLAHGGGHGADDGKVAGKLD
RLFHKVLPPFLDERSGAAARKKLFLGVLAAIFLSVSLAVVKLVVLKMLPFDNKSEFQVVL
DMPVGTPLEETARVLKDIGAVLQQVPEVTDYQAYAGTASPINFNGLVRQYYLRSEPEMGD
IQVNLVDKHHRSRQSHEIAVAVRAEIEAGARRAGGNAKVVEVPPGPPVMSPIVAEIYGPE
EAGRIAVAKQVRGVFEKAPDFTSVDDSVQADAEKTVLRVNQTKAAQLGVAQKDIVEVVRM
GLAGEDVTPAHNQDSKYEIPVRITLPAEVQSSLDALLRLKVRARSGALVPVSEVVEVRRL
AREKAIYHKDLLPVVYVYGDMGGDLDSPLYGMFAARGDIVGMNLDGLKGAGGTLADTFIR
QPADPYAGFSLKWDGEWQITYETFRDMGAAYGVGLILIYLLVVAHFKSYVTPLIIMAPIP
LTIIGVMPGHALLRSQFTATSMIGMIALAGIIVRNSILLVDFIKEETAKGMPFKEAIVTA
AAVRAKPIALTALAAMLGALFILDDPIFNGLAISLIFGILVSTLLTLVVIPVLYYATFKE
QQP