Protein Info for Dsui_3421 in Dechlorosoma suillum PS

Annotation: putative glycerate kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF13660: DUF4147
  • amino acids 15 to 238 (224 residues), 301.3 bits, E=4.7e-94
• PF05161: MOFRL
  • amino acids 318 to 426 (109 residues), 119 bits, E=1.1e-38

Best Hits

Swiss-Prot: 57% identical to TTUD4_AGRVI: Putative hydroxypyruvate reductase (ttuD) from Agrobacterium vitis

KEGG orthology group: K00050, hydroxypyruvate reductase [EC: 1.1.1.81] (inferred from 66% identity to amv:ACMV_26980)

Predicted SEED Role

"D-glycerate 2-kinase (EC 2.7.1.-)" in subsystem D-galactarate, D-glucarate and D-glycerate catabolism or Entner-Doudoroff Pathway (EC 2.7.1.-)

MetaCyc Pathways

• photorespiration I (5/9 steps found)
• photorespiration III (5/9 steps found)
• L-serine biosynthesis II (1/4 steps found)
• formaldehyde assimilation I (serine pathway) (6/13 steps found)

KEGG Metabolic Maps

• Glycine, serine and threonine metabolism
• Glyoxylate and dicarboxylate metabolism
• Lipopolysaccharide biosynthesis
• Nicotinate and nicotinamide metabolism
• Pentose phosphate pathway

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.-

Use Curated BLAST to search for 1.1.1.81 or 2.7.1.-

Sequence Analysis Tools

See G8QKL1 at UniProt or InterPro

Protein Sequence (439 amino acids)

>Dsui_3421 putative glycerate kinase (Dechlorosoma suillum PS)
MSAASQKQLAPDALLHNLLQAALAAADPARLVPPHLPDPASLPEGGRLVVVGAGKAAGAM
ARAVEEHWPGPLSGLVVTRYGHGLPCRRIEVVEAAHPVPDAAGEAAAARILEQVRGLTEK
DRVLALISGGGSALMAAPAPGVSLAQKRALTRALLLSGADIGEINCVRKHLSAVKGGRLA
AAAWPAPVLTLAISDVAGDDPSVIASGPTVADPTTCADALAVLARYGIEVPPEVAALLHS
GALETPKPGDPRLGRSDYRLIGRPQQSLLAAAEAARAAGITPLVLGDRVEGESKEVAKVM
AGLALACQDHGTPLAPPCVLLSGGETTVSVAPGAPLGRGGRNSEFLLALALALGGRPGIH
ALAADTDGIDGSEDNAGACIGPATLARAAAAGPDAQGHLAGHDAYGFFAGLGDLLLTGPT
RTNVNDFRAVLVLPGEDQD