Protein Info for Dsui_3354 in Dechlorosoma suillum PS

Annotation: adenine specific DNA methylase Mod

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 539 PF01555: N6_N4_Mtase" amino acids 65 to 390 (326 residues), 137.1 bits, see alignment E=4.5e-44

Best Hits

KEGG orthology group: None (inferred from 65% identity to bcb:BCB4264_A0972)

Predicted SEED Role

"Type III restriction-modification system methylation subunit (EC 2.1.1.72)" in subsystem Restriction-Modification System (EC 2.1.1.72)

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.72

Use Curated BLAST to search for 2.1.1.72

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QK05 at UniProt or InterPro

Protein Sequence (539 amino acids)

>Dsui_3354 adenine specific DNA methylase Mod (Dechlorosoma suillum PS)
MPTLHWVGKNKVVNHHHEVPFRLLDKQYSFTANKGTPANSTNNKIIHGDNLEALKSLLPE
FEGKVNCIYIDPPYNTGNEGWVYNDNVNDPKIKKWLGQVVGKEGEDLSRHDKWLCMMYPR
LKLLHRLLADEGSMWISIDDAAVTLLRPVMDEIFGAGKLIASNVWQKRYSRENREAIGDV
HEYILVYSKTPAAFKLSRNKIPIDEKQAKVYRNPNNDPKGRWRPIPMTAQAGHATADQFY
EIISPSGKKFKPSEGRCWGISEATFKTLLSEGRIYFGKKGNSQPNIIRYLSEVEGVVPWT
WWPHEEVGNTDEATKDLMAIFGGASGFDTTPKPVRLIERVLQICSQRNSLILDSFGGSGT
TAHAVLKLNAQDGGNRRFILCEMMDYAETITAERIRRVIDGYGEGNKVVAGTGGGFDFFK
VGEALFKEDKNLNEEVGAEAIRGYVAYTENIPTEKRWDTENAVSPYALGSTDTALCVFYY
EKDRVTTLDIDFLGQLKIKNLPSRPEQFVIYADKCALDKDFLYKHGITFKRIPRDITRF